Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
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Journal ArticleDOI
Environmental applications and potential health implications of quantum dots
Farhan Ahmad,Alok K. Pandey,Amanda B. Herzog,Joan B. Rose,Charles P. Gerba,Charles P. Gerba,Syed A. Hashsham +6 more
TL;DR: Systematic studies on the impact of QDs on environment and health may facilitate its safe use for environmental applications and provide toxicity data important to human health.
Journal ArticleDOI
Immune Response Induced by Fluorescent Nanocrystal Quantum Dots In Vitro and In Vivo
TL;DR: Results indicated that QDs covered with nucleotides caused the peritoneal inflammation in vivo via activation of PMphi and probably nonimmune cells, and it is proposed here that all nanotechnology researchers should confirm the biological responses of their nanoscale products.
Journal ArticleDOI
Multi-functional mesoporous β-Ga2O3: Cr3+ nanorod with long lasting near infrared luminescence for in vivo imaging and drug delivery
TL;DR: The long lasting luminescent β-Ga2O3: Cr3+ nanorod allows detection in deep organs hours after injection based on the fact that it exhibits more than 72 h afterglow in the wavelength range of 650-850 nm after the cessation of ultraviolet light irradiation as mentioned in this paper.
Journal ArticleDOI
Efficient and Rapid Divergent Synthesis of Ethylene Oxide-Containing Dendrimers through Catalyst-Free Click Chemistry
TL;DR: In this paper, the third and fourth generation ethylene oxide-containing dendrimers containing triazole units were prepared divergently through metal-free Huisgen 1,3-dipolar cycloaddition (click) reaction between activated disubstituted alkyne and terminal azide groups.
Book ChapterDOI
Nanoparticles in the Lung
TL;DR: In this article, the same basic principles of physical and biological science apply to NP toxicology regardless of the source or intended application of the material, and the authors emphasize the following areas: (1) physical properties of NPs that make them of interest for both materials science and toxicology; (2) plausible lung exposures to medical, manufactured, and incidental NPs; (3) known whole-organism effects of environmental ultrafine and manufactured NPs, and (4) the cellular and molecular evidence for unique toxicities associated with NPs compared to larger particles of the same
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.