Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
Citations
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Near-Infrared Quantum Dots as Optical Probes for Tumor Imaging
TL;DR: The goal of this review is to provide readers the basics of NIR-emitting QDs, the bioconjugate chemistry ofQDs, and their applications for diagnostic tumor imaging.
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Nanowire-Based Sensors for Biological and Medical Applications
TL;DR: It is expected that nanowires will contribute significantly to the development of biological and medical sensors in the immediate future with the advantages of ultra-sensitivity and the ease of fabrication.
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Single molecule localization microscopy for superresolution
TL;DR: A brief overview of superresolution microscopy is provided, followed by a detailed discussion of STORM, including practical guidelines for sample preparation designed to help to make the technique more accessible to the non-specialist.
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CT imaging of myocardial scars with collagen-targeting gold nanoparticles
TL;DR: A collagen-targeting gold nanoparticle-based approach is presented that enables the imaging of myocardial scars via CT scans in a rodent model and would enable clinicians to judge the recovery potential of the myocardium more accurately than the current CT-scan based approaches.
Regulation and Risk Assessment of Nanomaterials - Too Little, Too Late?
TL;DR: In this article, the authors investigate whether existing regulation is adequate in the short and the long term, explore the feasibility of risk assessment for the purpose of dealing with the complex emerging risks of nanomaterials, and finally, provide recommendations on how to govern nanotechnologies.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
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Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
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Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
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Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.