Journal ArticleDOI
Noninvasive Imaging of Quantum Dots in Mice
TLDR
Long-term experiments demonstrated that these quantum dots remain fluorescent after at least four months in vivo, using only quantum dots for detection.About:
This article is published in Bioconjugate Chemistry.The article was published on 2004-01-01. It has received 1153 citations till now. The article focuses on the topics: Quantum dot & Fluorescence-lifetime imaging microscopy.read more
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Dissertation
Nanocristaux à luminescence persistante : nouveaux concepts pour l'imagerie in vivo
TL;DR: In this paper, a new generation of nanocristaux is introduced, which can be used for the detection of luminescence persistante in vivo in vivo, a traversing les tissus de l'animal.
Book ChapterDOI
Applications of Quantum Dots for Fluorescence Imaging in Biomedical Research
ShuQi Wang,Matin Esfahani,Dusan Sarenac,Bettina Cheung,Aishwarya Vasudevan,Fatih Inci,Utkan Demirci +6 more
Abstract: Biomedical research is currently one of fastest growing areas with advanced technologies such as microfluidics, fluorescence imaging, and microelectromechanical systems (MEMS). For fluorescence imaging, conventional organic dyes (e.g., Rhodamine B) are extensively used. Recently, quantum dots (QDs), due to their special optical properties, are gaining momentum in their role in biomedical research such as in the development of biosensors, clinical diagnosis, and basic immunological studies. QDs are semiconductor nanoparticles with a diameter of 5–50 nm, including a metal core and an insulator surface. Because of their nanoscale structure, QDs have strictly confined electronic wave functions, which confer QDs with unique optical properties such as high luminescence intensity, high molar extinction coefficient, size-tunable emission
Dissertation
Développement de nanoémetteurs polarisés pour leur application comme sondes d'orientation
TL;DR: In this article, the luminescence of nanoparticules luminescentes is used to predict the transition of phase of the matrices hexagonale and to detect defauts structuraux.
References
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Journal ArticleDOI
Semiconductor Nanocrystals as Fluorescent Biological Labels
TL;DR: Semiconductor nanocrystals prepared for use as fluorescent probes in biological staining and diagnostics have a narrow, tunable, symmetric emission spectrum and are photochemically stable.
Journal ArticleDOI
Quantum Dot Bioconjugates for Ultrasensitive Nonisotopic Detection
Warren C. W. Chan,Shuming Nie +1 more
TL;DR: Highly luminescent semiconductor quantum dots (zinc sulfide-capped cadmium selenide) have been covalently coupled to biomolecules for use in ultrasensitive biological detection and these nanometer-sized conjugates are water-soluble and biocompatible.
Journal Article
Long-Circulating and Target-Specific Nanoparticles: Theory to Practice
TL;DR: The surface mechanisms, which affords red blood cells long-circulatory lives and the ability of specific microorganisms to evade macrophage recognition, are explored and the rational approaches in the design as well as the biological performance of such constructs are assessed.
Journal ArticleDOI
Nanoparticles in cancer therapy and diagnosis
TL;DR: The in vivo fate of these systems, after intravascular or tumoral administration, is discussed, as well as the mechanism involved in tumor regression, and the application of nanoparticles in imaging for cancer diagnosis is focused on.
Journal ArticleDOI
Effect of pegylation on pharmaceuticals
J. Milton Harris,Robert B. Chess +1 more
TL;DR: How PEGylation can result in drugs that are often more effective and safer, and which show improved patient convenience and compliance are reviewed.