Open Access
Phase solubility techniques
T K Higuchi,A Connors +1 more
- Vol. 4, pp 212-217
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The article was published on 1965-01-01 and is currently open access. It has received 2515 citations till now. The article focuses on the topics: Phase (matter) & Solubility.read more
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Structural analysis and cytotoxicity of host-guest inclusion complexes of cannabidiol with three native cyclodextrins
Pin Lv,Dongjing Zhang,Guo Mengbi,Jing Liu,Xuan Chen,Guo Rong,Xu Yanping,Qingying Zhang,Ying Liu,Guo Hongyan,Yang Ming +10 more
TL;DR: It is noteworthy that significant increases in the water solubility and in vitro cytotoxicity of cannabidiol were found in the form of inclusion complex with three natural cyclodextrins compared with free cannabdiol.
Journal ArticleDOI
Water soluble progesterone–hydroxypropyl-β-cyclodextrin complex for injectable formulations
TL;DR: In this article, Choi et al. developed a production process in which the residual unreacted β-cyclodextrin is separated from the HPBCD by the formation of the insoluble inclusion complex.
Journal ArticleDOI
Characterisation of Gliclazide-PEG 8000 Solid Dispersions
TL;DR: In this article, the authors compared gliclazide solid dispersions (SDs) with polyethylene glycol (PEG) 8000 and compared them with SDs in PEG 6000.
Journal ArticleDOI
Complexation and Full Characterization of the Tretinoin and Dimethyl-βeta-Cyclodextrin Complex
Andreia Ascenso,Rita C. Guedes,Raul J. Bernardino,Hermínio P. Diogo,Filomena A. Carvalho,Nuno C. Santos,Aida M. Silva,Helena Cabral Marques +7 more
TL;DR: The aim of this work is to prepare tretinoin/dimethyl-beta-cyclodextrin complexes and fully characterize them through various analytical techniques and it is proposed that the structure of the drug included into the cyclodesxtrin corresponds to the side chain including the functional group COOH.
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Cyclodextrin as a potential drug carrier in salbutamol dry powder aerosols: the in-vitro deposition and toxicity studies of the complexes.
TL;DR: GCD and DMCD are able to promote salbutamol delivery in dry powder inhaler compared to a formulation containing lactose and GCD is relatively safe in the rat if the amount of GCD in the formulation is similar to this experiment.