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Phase solubility techniques
T K Higuchi,A Connors +1 more
- Vol. 4, pp 212-217
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The article was published on 1965-01-01 and is currently open access. It has received 2515 citations till now. The article focuses on the topics: Phase (matter) & Solubility.read more
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Functional food product development.
Jim Smith,Edward Charter +1 more
TL;DR: The use of functional plant ingredients for the development of efficacious functional foods and the stability and release of encapsulated nutraceuticals and their applications are discussed.
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Inclusion complex of erlotinib with sulfobutyl ether-β-cyclodextrin: Preparation, characterization, in silico, in vitro and in vivo evaluation.
Naresh Devasari,Chander Parkash Dora,Charan Singh,Sharan K. Paidi,Vivek Kumar,Masilamani Elizabeth Sobhia,Sarasija Suresh +6 more
TL;DR: In vitro dissolution and in vivo bioavailability studies further confirmed the ERL-SBE-β-CD as a valuable approach to enhance ERL oral bioavailability with 3.6-fold increase in relative oral bio availability with higher Cmax and AUC0-∞ in comparison to pure ERL.
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Antibacterial mechanism of artemisinin / beta-cyclodextrins against methicillin-resistant Staphylococcus aureus (MRSA).
TL;DR: The obtained results enable the potential use of ART/β-CDs-IC in the field of antimicrobial and indicated the membrane permeability of MRSA can be increased by the complexes.
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Evolution of Choice of Solubility and Dissolution Media After Two Decades of Biopharmaceutical Classification System
Nadia Araci Bou-Chacra,Katherine Jasmine Curo Melo,Ivan Andrés Cordova Morales,Erika S. Stippler,Filippos Kesisoglou,Mehran Yazdanian,Raimar Löbenberg +6 more
TL;DR: The purpose of this review is to summarize the evolution of the media used for determining solubility and dissolution and how this can be used in modern drug development.
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Improvement of water solubility of sulfamethizole through its complexation with β- and hydroxypropyl-β-cyclodextrin: Characterization of the interaction in solution and in solid state
Beatriz Pose-Vilarnovo,Iliana Perdomo-López,Magdalena Echezarreta-López,Patricia Schroth-Pardo,Ernesto Estrada,Juan J. Torres-Labandeira +5 more
TL;DR: Sulfamethizole moiety included in the cyclodextrin was the thiadiazole group and MM2 calculations, either in vacuum or in the presence of a solvent, support this structure.