Open Access
Phase solubility techniques
T K Higuchi,A Connors +1 more
- Vol. 4, pp 212-217
About:
The article was published on 1965-01-01 and is currently open access. It has received 2515 citations till now. The article focuses on the topics: Phase (matter) & Solubility.read more
Citations
More filters
Journal ArticleDOI
Characterization, phase-solubility, and molecular modeling of inclusion complex of 5-nitroindazole derivative with cyclodextrins
Carolina Jullian,Javier Morales-Montecinos,Gerald Zapata-Torres,Benjamín Aguilera,Jorge Rodríguez,Vicente J. Arán,Claudio Olea-Azar +6 more
TL;DR: The slightly water-soluble 5-nitroindazole derivative (5-NI) and its inclusion with either beta-cyclodextrin (betaCD) or Heptakis (2,6-di-O-methyl)-beta- cyclodextrine (DM betaCD) were investigated and a 1:1 stoichiometry has been proposed for the complexes.
Journal ArticleDOI
Solubilty and dissolution studies of antifungal drug:hydroxybutenyl-β-cyclodextrin complexes
TL;DR: The solubilization of these antifungal drugs by HBenBCD to other cyclodextrin derivatives with different substituents under identical experimental conditions was compared and found that the amount of drugsolubilized was in some cases influenced strongly by the nature of the cyclodesxtrin.
Journal ArticleDOI
Effect of hydroxypropyl-β-cyclodextrin on the antimicrobial action of preservatives
TL;DR: The loss in activity by complex formation correlated with the bound fraction, thus suggesting that the appropriate antimicrobial substance for the preservation of cyclodextrin solutions can be selected according to the results of this study.
Journal ArticleDOI
Microencapsulation of caffeic acid phenethyl ester and caffeic acid phenethyl amide by inclusion in hydroxypropyl-β-cyclodextrin.
E. Manuela Garrido,E. Manuela Garrido,Ana S. Cerqueira,Ana S. Cerqueira,Daniel Chavarria,Tiago H. Silva,Fernanda Borges,Jorge Garrido,Jorge Garrido +8 more
TL;DR: The aqueous solubility increased notably, proving that HP-β-CD can be potentially useful to improve the biological, chemical and physical properties of CAPE and CAPA.
Journal ArticleDOI
Enhancement of oral bioavailability of anti-HIV drug rilpivirine HCl through nanosponge formulation*
TL;DR: The microwave mediated approach offers a comfortable dosing zone for AIDs patients, negating the requirement of consuming the formulation in a fed state due to enhancement in drugs’ oral bioavailability.