Open Access
Phase solubility techniques
T K Higuchi,A Connors +1 more
- Vol. 4, pp 212-217
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The article was published on 1965-01-01 and is currently open access. It has received 2515 citations till now. The article focuses on the topics: Phase (matter) & Solubility.read more
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Cyclodextrins as a useful tool for bioconversions in plant cell biotechnology
TL;DR: The possibilities for cyclodextrin facilitated bioconversions by freely suspended and/or immobilized plant cells or plant enzymes are demonstrated and fourcyclodextrins were used to improve the solubility of podophyllotoxin.
Journal ArticleDOI
Anticancer Efficacy of Self-Nanoemulsifying Drug Delivery System of Sunitinib Malate
Saad M. Alshahrani,Abdullah S. Alshetaili,Ahmed Alalaiwe,Bader B. Alsulays,Md. Khalid Anwer,Ramadan Al-Shdefat,Ramadan Al-Shdefat,Faisal Imam,Faiyaz Shakeel +8 more
TL;DR: The results of this study showed the great potential of SNEDDS in the enhancement of in vitro dissolution rate and anticancer efficacy of poorly soluble drug such as SM.
Journal ArticleDOI
In Vitro Enhanced Skin Permeation and Retention of Imiquimod Loaded in β-Cyclodextrin Nanosponge Hydrogel.
Monica Argenziano,Ádám Haimhoffer,Chiara Bastiancich,Laszlo Jicsinszky,Fabrizio Caldera,Francesco Trotta,Sara Scutera,Daniela Alotto,Mara Fumagalli,Tiziana Musso,Carlotta Castagnoli,Roberta Cavalli +11 more
TL;DR: This work aims at developing a nanomedicine-based topical formulation, carrying IMQ to control the scarring process for the treatment of aberrant wounds, loaded in β-cyclodextrin-based nanosponges and dispersed in a hydrogel suitable for dermal application.
Formulation and evaluation of mouth dissolving tablets of oxcarbazepine
TL;DR: In this article, the mouth dissolving tablets of oxcarbazepine were prepared using two different technologies, direct compression method and solid dispersion technology, and the results compared for both the technologies showed that the oxcarbasepine tablets prepared using solid dispersive technology was found to have good technological properties and satisfying and reproducible drug dissolution profiles.
Journal ArticleDOI
Interaction of naproxen with β-cyclodextrin in solution and in the solid state
Francisco J. Otero-Espinar,S. Anguiano-Igea,N. García-González,J. L. Vila-Jato,José Blanco-Méndez +4 more
TL;DR: The behavior of the inclusion complex of naproxen with β-cyclodextrin was studied by molecular modelling using interactive computer graphics, solubility diagrams at different temperatures and pH values, infrared spectroscopy and differential scanning calorimetry.