Open Access
Phase solubility techniques
T K Higuchi,A Connors +1 more
- Vol. 4, pp 212-217
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The article was published on 1965-01-01 and is currently open access. It has received 2515 citations till now. The article focuses on the topics: Phase (matter) & Solubility.read more
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Solubility and Mass and Nuclear Magnetic Resonance Spectroscopic Studies on Interaction of Cyclosporin A with Dimethyl‐α‐ and ‐β‐Cyclodextrins in Aqueous Solution
TL;DR: In this paper, the interaction of cyclosporin A (CsA) with dimethyl-alpha- and -beta-cyclodextrins (DM-α-Cyd and DM-beta-CyD) was investigated by the solubility method, electrospray ionization mass spectrometry (ESI-MS) and 1H-nuclear magnetic resonance spectroscopy (1H NMR).
Journal ArticleDOI
The effect of some natural polymers on the solubility and dissolution characteristics of nifedipine
TL;DR: In this paper, the effect of natural polymers such as water-soluble gelatin and egg albumin on the solubility and dissolution characteristics of nifedipine has been studied.
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Stent coating by electrospinning with chitosan/poly-cyclodextrin based nanofibers loaded with simvastatin for restenosis prevention.
Dyhia Kersani,Justine Mougin,Marco Lopez,Stephanie Degoutin,Nicolas Tabary,Frederic Cazaux,Ludovic Janus,Mickaël Maton,Feng Chai,Jonathan Sobocinski,Nicolas Blanchemain,Bernard Martel +11 more
TL;DR: A stent covered by nanofibers (NFs) produced by electrospinning, loaded with simvastatin (SV), a drug commonly used for restenosis prevention is developed, whose efficiency will be investigated in a further in vivo study.
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Effect of antioxidant activity of caffeic acid with cyclodextrins using ground mixture method
TL;DR: Caffeic acid /β-cyclodextrin (molar ratio = 1/1), the aromatic ring of the caffeic acid molecule appears to be included from the wider to the narrower rim of the ring of βCD.
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Use of cyclodextrins as solubilizing agents for simvastatin: effect of hydroxypropyl-β-cyclodextrin on lactone/hydroxyacid aqueous equilibrium.
Francesca Ungaro,Concetta Giovino,Ovidio Catanzano,Agnese Miro,Andrea Mele,Fabiana Quaglia,Maria Immacolata La Rotonda +6 more
TL;DR: In this article, a reverse-phase HPLC method was used to identify and quantify simvastatin and SVA in the presence of cyclodextrins (CDs) and showed that the aqueous SVL/SVA equilibrium is shifted versus the hydroxyacid form.