Open Access
Phase solubility techniques
T K Higuchi,A Connors +1 more
- Vol. 4, pp 212-217
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The article was published on 1965-01-01 and is currently open access. It has received 2515 citations till now. The article focuses on the topics: Phase (matter) & Solubility.read more
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Self-assembly of cyclodextrins: the effect of the guest molecule.
TL;DR: The role of guest molecule nature (i.e. its structural and functional peculiarities) in cyclodextrin complex aggregation as well as in the aggregate stability assessed using a cellophane membrane permeability assay was explored in this article.
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Transdermal delivery of zidovudine (AZT): the effects of vehicles, enhancers, and polymer membranes on permeation across cadaver pig skin
TL;DR: The purpose of this study was to investigate the effects of vehicles, enhancers, and polymer membranes on 3-azido-3-deoxythymidine (AZT) permeation across cadaver pig skin and the results obtained will be helpful in the development of an AZT transdermal drug delivery system.
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Microbial transformations in a cyclodextrin medium. Part 2. Reduction of androstenedione to testosterone by Saccharomyces cerevisiae
TL;DR: A mechanism whereby CDs reduce the effective inhibitory concentrations of substrate and product as well as facilitate transport of the complexed substrate through the yeast cell wall has been suggested for the CD-promoted biotransformation.
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Encapsulation in cyclodextrins to widen the applications of essential oils
TL;DR: In this paper, essential oils encapsulation in cyclodextrins has been studied and shown to increase the aqueous solubility of essential oils up to 16-fold and reduce photodegradation rates up to 44-fold while ensuring a gradual release.
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Modified β-Cyclodextrin (SBE7-β-CyD) with Viscous Vehicle Improves the Ocular Delivery and Tolerability of Pilocarpine Prodrug in Rabbits
TL;DR: In this article, the effects of coadministered SBE7-beta-CyD with and without polyvinyl alcohol (PVA) on the miotic response and eye irritation of the prodrug were investigated in pigmented rabbits.