Predicting Age Using Neuroimaging: Innovative Brain Ageing Biomarkers.
James H. Cole,Katja Franke +1 more
TLDR
Evidence supporting the use of neuroimaging-based 'brain age' as a biomarker of an individual's brain health is presented and controversies surrounding brain age are discussed.About:
This article is published in Trends in Neurosciences.The article was published on 2017-12-01 and is currently open access. It has received 516 citations till now.read more
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Hallmarks of Brain Aging: Adaptive and Pathological Modification by Metabolic States.
TL;DR: An overview of the cellular and molecular biology of brain aging, how those processes interface with disease-specific neurodegenerative pathways, and how metabolic states influence brain health is provided.
Journal ArticleDOI
Establishment of Best Practices for Evidence for Prediction: A Review.
TL;DR: Various measures of predictive performance and the limitations of some commonly used measures are discussed, with a focus on the importance of using multiple measures when assessing performance.
Journal ArticleDOI
Ten Years of BrainAGE as a Neuroimaging Biomarker of Brain Aging: What Insights Have We Gained?
Katja Franke,Christian Gaser +1 more
TL;DR: This review summarizes all studies published within the last 10 years that have established and utilized the BrainAGE method to evaluate the effects of interaction of genes, environment, life burden, diseases, or life time on individual neuroanatomical aging.
Journal ArticleDOI
Common brain disorders are associated with heritable patterns of apparent aging of the brain
TL;DR: Using structural MRI data from 45,615 individuals aged 3-96 years, distinct patterns of apparent brain aging in several brain disorders are demonstrated and genetic pleiotropy between apparent brain Aging in healthy individuals and common brain disorders is revealed.
Journal ArticleDOI
Brain age and other bodily ‘ages’: implications for neuropsychiatry
TL;DR: Recent neuroimaging research into brain ageing and the use of other bodily ageing biomarkers, including telomere length, the epigenetic clock, and grip strength are outlined.
References
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