Applied Science Private University

About: Applied Science Private University is a education organization based out in Amman, Jordan. It is known for research contribution in the topics: Catalysis & Population. The organization has 4124 authors who have published 5299 publications receiving 116167 citations.

Design and evaluation of effervescent floating tablets based on hydroxyethyl cellulose and sodium alginate using pentoxifylline as a model drug

Abstract: The aim of this work was to design and evaluate effervescent floating gastro-retentive drug delivery matrix tablets with sustained-release behavior using a binary mixture of hydroxyethyl cellulose and sodium alginate. Pentoxifylline was used as a highly water-soluble, short half-life model drug with a high density. The floating capacity, swelling, and drug release behaviors of drug-loaded matrix tablets were evaluated in 0.1 N HCl (pH 1.2) at 37°C±0.5°C. Release data were analyzed by fitting the power law model of Korsmeyer-Peppas. The effect of different formulation variables was investigated, such as wet granulation, sodium bicarbonate gas-forming agent level, and tablet hardness properties. Statistical analysis was applied by paired sample t-test and one-way analysis of variance depending on the type of data to determine significant effect of different parameters. All prepared tablets through wet granulation showed acceptable physicochemical properties and their drug release profiles followed non-Fickian diffusion. They could float on the surface of dissolution medium and sustain drug release over 24 hours. Tablets prepared with 20% w/w sodium bicarbonate at 50-54 N hardness were promising with respect to their floating lag time, floating duration, swelling ability, and sustained drug release profile.

Alma follows streaming of dense gas down to 40 pc from the supermassive black hole in ngc 1097

Abstract: We present a kinematic analysis of the dense gas in the central 200 parsecs of thenearby galaxy NGC1097, based on Cycle 0 observations with the Atacama LargeMillimeter/sub-millimeter Array (ALMA)

A GIS-based multi-criteria decision making method for the potential assessment and suitable sites selection of PV and CSP plants

Abstract: By combining geographic information systems (GIS) and multi-criteria decision making (MCDM) method, this paper presents a framework to evaluate the suitable location and technical potentials for large-scale solar photovoltaic (PV) and concentrated solar power (CSP) plants. With the assist of spatial tools, the potential locations are identified by extracting restrictive criteria (e.g. protected area, land cover, transport infrastructure, and orography). Using MCDM, the land suitability for PV and CSP plants is evaluated with the comprehensive consideration of different factors, such as climate, orography, water availability, and location, where factor weights are calculated by the analytic hierarchy process (AHP) method. The study framework is illustrated by Ningxia, China, a key energy project area along the Belt and Road with abundant solar radiation. The obtained results suggested that the middle area of Ningxia is recommended for the solar power plant deployment. Besides, due to the limitation of water resource availability, PV technology is more appropriate for the study area than CSP technology. The estimated total technical potentials of PV and CSP systems could be 443 TWh/year and 308 TWh/year, indicating great potential for future solar energy development to enhance the renewable energy supply and participate in energy cooperation with the other regions. Moreover, sensitivity analysis is conducted to investigate the impacts of system efficiency variation on energy output. The results can be used for the identification of the potential areas for solar power plant installation, as well as support for the synergic expansion of generation plants and the power grid.