Conservatoire national des arts et métiers

About: Conservatoire national des arts et métiers is a education organization based out in Paris, France. It is known for research contribution in the topics: Population & Context (language use). The organization has 3573 authors who have published 7127 publications receiving 141430 citations. The organization is also known as: CNAM & Conservatoire des arts et métiers.

New Thin Piezoelectric Plate Models

Abstract: Early investigations on piezoelectric plates were based on a priori mechanical and experimental considerations. They assume plane stress and consider only transverse components of electric displace...

The First Official REPERE Evaluation.

Abstract: The REPERE Challenge aims to support research on people recognition in multimodal conditions. Following a 2012 dryrun [1], the first official evaluation of systems has been conducted at the beginning of 2013. To both help system development and assess the technology progress a specific corpus is developed. It current totals at 30 hours of video with multimodal annotations. The systems have to answer the following questions: Who is speaking? Who is present in the video? What names are cited? What names are displayed? The challenge is to combine the various informations coming from the speech and the images.

Fatigue crack growth from small to long cracks in very-high-cycle fatigue with surface and internal fish-eye failures for ferrite-perlitic low carbon steel SAE 8620

Abstract: In recent years, the importance of knowing the materials behavior under very-high-cycle fatigue has been pointed out by many research laboratories around the world. An important failure phenomenon has been seen between 10 6 and 10 8 cycles, where the failure initiation may switch location from the specimen surface to an interior “fish-eye”. The Paris–Hertzberg–McClintock crack growth rate law, d a / d N = b ( Δ K eff / E b ) 3 , will demonstrate that crack growth is not of significant portion of total life if over 10 7 cycles for a low carbon steel SAE 8620, with ferrite-pearlite microstructure. In this discussion, the presence of closure will be explored for a range of transition sizes from small to long crack and various load ratios. Cracks initiating at both surface and internal sites will also be considered. Finally, the stress intensity factor at final failure for internal failure will be estimated to see its impact.

Multitarget Therapeutic Strategies for Alzheimer's Disease: Review on Emerging Target Combinations.

Abstract: Neurodegenerative diseases represent nowadays one of the major health problems. Despite the efforts made to unveil the mechanism leading to neurodegeneration, it is still not entirely clear what triggers this phenomenon and what allows its progression. Nevertheless, it is accepted that neurodegeneration is a consequence of several detrimental processes, such as protein aggregation, oxidative stress, and neuroinflammation, finally resulting in the loss of neuronal functions. Starting from these evidences, there has been a wide search for novel agents able to address more than a single event at the same time, the so-called multitarget-directed ligands (MTDLs). These compounds originated from the combination of different pharmacophoric elements which endowed them with the ability to interfere with different enzymatic and/or receptor systems, or to exert neuroprotective effects by modulating proteins and metal homeostasis. MTDLs have been the focus of the latest strategies to discover a new treatment for Alzheimer's disease (AD), which is considered the most common form of dementia characterized by neurodegeneration and cognitive dysfunctions. This review is aimed at collecting the latest and most interesting target combinations for the treatment of AD, with a detailed discussion on new agents with favorable in vitro properties and on optimized structures that have already been assessed in vivo in animal models of dementia.

Swollen liquid crystals (SLCs): a versatile template for the synthesis of nano structured materials

Abstract: Liquid crystal (LCs) is the state of matter that exhibits properties between a conventional liquid and solid crystals. Liquid crystals mainly can be classified into two types: thermotropic and lyotropic liquid crystals. A thermotropic liquid crystal shows properties that are dependent on temperature conditions. On the other hand in lyotropic liquid crystals (LLCs), the amphiphiles are dissolved in a solvent and exhibit liquid crystalline properties in certain concentration ranges. In the literature, lot of reviews have been presented on thermotropic and lyotropic liquid crystals (LLCs). But nowadays, swollen liquid crystals (SLCs) have become a much more important area of research because of their easily tunable properties, their stability and versatility of the system. Swollen liquid crystals (SLCs) consist of infinite liquid crystalline non polar cylinders organized on a hexagonal lattice in a polar medium and are prepared with the proper ratios of salted water and non polar solvents with cationic or anionic or non ionic surfactants and co surfactants i.e. water : oil : surfactant : cosurfactant. In this review article, we will briefly discuss the synthesis of swollen liquid crystals (SLCs), factors affecting their stability, different kinds of nanomaterials such as metallic, bimetallic, polymeric nanostructures synthesized inside swollen liquid crystals (SLCs) using different methods and the effect of swollen liquid crystal (SLC) confinement on the final morphology of nanomaterials with their potential applications.