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Institution

Keele University

EducationNewcastle-under-Lyme, United Kingdom
About: Keele University is a education organization based out in Newcastle-under-Lyme, United Kingdom. It is known for research contribution in the topics: Population & Stars. The organization has 11318 authors who have published 26323 publications receiving 894671 citations. The organization is also known as: Keele University.


Papers
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Journal ArticleDOI
TL;DR: This review highlights how recent methodological advances in the identification and characterization of G-quadruplexes in vivo as well as in vitro, and at a much higher resolution and throughput, have opened new doors to investigate the potential functions and applications in basic and applied biosciences.

274 citations

Journal ArticleDOI
TL;DR: It is argued that the structural validity of the simulation model—right behavior for the right reasons—is a stringent measure to build confidence in a simulation model regardless of how well the model passes behavior validity tests.

274 citations

Journal ArticleDOI
TL;DR: In this paper, an investigation of the incidence and impact of physical, verbal and property-violation bullying in 25 secondary schools within a partnership operating with Keele University is presented.
Abstract: This paper outlines an investigation of the incidence and impact of physical, verbal and property-violation bullying in 25 secondary schools within a partnership operating with Keele University. The investigation also considers the impact of antisocial behaviour on pupils and the effectiveness of intervention to secure improved behaviour patterns. Evidence shows that in any year 75 per cent of pupils are bullied but that severe and repeated bullying is likely to be perpetrated and suffered by about seven per cent of pupils. Four behaviour patterns can be identified: bullies, bullies who are also victims, victims and non-participants, and the link between behaviour and factors in developing self-esteem is explored. Successful intervention requires a change of attitude on the part of both pupils and the community, a willingness to report events, and an understanding of respect for personal space.

274 citations

Journal ArticleDOI
TL;DR: Queen-derived hydrocarbon labels inform workers about the presence of a fertile queen and thereby regulate worker reproduction, which induces workers to refrain from reproducing.
Abstract: A hitherto largely unresolved problem in behavioral biology is how workers are prevented from reproducing in large insect societies with high relatedness. Signals of the queen are assumed to inform the nestmates about her presence in the colony, which leads to indirect fitness benefits for workers. In the ant Camponotus floridanus, we found such a signal located on queen-laid eggs. In groups of workers that were regularly provided with queen-laid eggs, larvae, and cocoons, with larvae and cocoons alone, or with no brood, only in the groups with queen-laid eggs did workers not lay eggs. Thus, the eggs seem to inform the nestmates about the queen's presence, which induces workers to refrain from reproducing. The signal on queen-laid eggs is presumably the same that enables workers to distinguish between queen- and worker-laid eggs. Despite their viability, the latter are destroyed by workers when given a choice between both types. Queen- and worker-laid eggs differ in their surface hydrocarbons in a way similar to the way fertile queens differ from workers in the composition of their cuticular hydrocarbons. When we transferred hydrocarbons from the queen cuticle to worker-laid eggs, the destruction of those eggs was significantly mitigated. We conclude that queen-derived hydrocarbon labels inform workers about the presence of a fertile queen and thereby regulate worker reproduction.

273 citations

Journal ArticleDOI
TL;DR: Systematic review and meta-analysis of randomized controlled trials of adequate acupuncture found acupuncture that meets criteria for adequate treatment is significantly superior to sham acupuncture and to no additional intervention in improving pain and function in patients with chronic knee pain.
Abstract: and study validity was assessed using a modification of a previously published instrument. Results. Thirteen RCTs were included, of which eight used adequate acupuncture and provided WOMAC outcomes, so were combined in meta-analyses. Six of these had validity scores of more than 50%. Combining five studies in 1334 patients, acupuncture was superior to sham acupuncture for both pain (weighted mean difference in WOMAC pain subscale score ¼ 2.0, 95% CI 0.57–3.40) and for WOMAC function subscale (4.32, 0.60–8.05). The differences were still significant at long-term follow-up. Acupuncture was also significantly superior to no additional intervention. There were insufficient studies to compare acupuncture with other sham or active interventions. Conclusions. Acupuncture that meets criteria for adequate treatment is significantly superior to sham acupuncture and to no additional intervention in improving pain and function in patients with chronic knee pain. Due to the heterogeneity in the results, however, further research is required to confirm these findings and provide more information on long-term effects.

273 citations


Authors

Showing all 11402 results

NameH-indexPapersCitations
George Davey Smith2242540248373
Simon D. M. White189795231645
James F. Wilson146677101883
Stephen O'Rahilly13852075686
Wendy Taylor131125289457
Nicola Maffulli115157059548
Georg Kresse111430244729
Patrick B. Hall11147068383
Peter T. Katzmarzyk11061856484
John F. Dovidio10946646982
Elizabeth H. Blackburn10834450726
Mary L. Phillips10542239995
Garry P. Nolan10447446025
Wayne W. Hancock10350535694
Mohamed H. Sayegh10348538540
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202344
2022155
20211,473
20201,377
20191,178
20181,106