Institution
Keele University
Education•Newcastle-under-Lyme, United Kingdom•
About: Keele University is a education organization based out in Newcastle-under-Lyme, United Kingdom. It is known for research contribution in the topics: Population & Stars. The organization has 11318 authors who have published 26323 publications receiving 894671 citations. The organization is also known as: Keele University.
Topics: Population, Stars, Health care, Context (language use), Politics
Papers published on a yearly basis
Papers
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TL;DR: In this article, the structural and functional aspects of SP-A and SP-D with emphasis on their roles in controlling pulmonary infection, allergy and inflammation are discussed, and a recently proposed model based on studies with the calreticulin-CD91 complex as a receptor for SP-a andSP-D in naive lungs which would help minimise the potential damage that continual low level exposure to pathogens, allergens and apoptosis can cause.
490 citations
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TL;DR: Evidence is provided that increasing age in the elderly population is not associated with any change in the overall prevalence of pain, although the pattern of pain prevalence in different body regions does change with age.
Abstract: Although pain is experienced at all ages, there is uncertainty about the pattern of its occurrence in older people. We have investigated the prevalence of three aspects of self-reported pain-occurrence of any recent pain, number and location of pain sites, and interference with daily life-to determine their association with age in older people. A cross-sectional postal survey of all adults aged 50 years and over registered with three general practices (n = 11230) in North Staffordshire using self-complete questionnaires was conducted. Respondents' gender, age, employment status, socio-economic classification, and general health status were gathered to characterise the population under study. The location of any recent pain (past 4 weeks) was recorded on a full-body manikin and pain interference was based on a single question. Completed questionnaires were received from 7878 respondents (adjusted response of 71.3%). The 4-week prevalence of any pain was 72.4%; similar across 10-year age-groups, and higher in females than males. In those with pain the median number of painful areas (from 44) was 6, and 12.5% of the responding population were classified as having widespread pain, both figures similar across age-groups. Most regional pains showed a decline in prevalence in the older age-groups, the exceptions being the lower limb regions (hip, knee, foot). Pain that interfered with daily activities was reported by 3002 (38.1%) respondents overall. There was a clear age-related rise in this prevalence with age up to and including the oldest group. Within each regional pain subgroup, the proportion of people who also reported pain interference rose with age. Our study has provided evidence that increasing age in the elderly population is not associated with any change in the overall prevalence of pain, although, as previous studies have suggested, the pattern of pain prevalence in different body regions does change with age. More importantly the extent to which pain interferes with everyday life increases incrementally with age up to the oldest age-group in the community-dwelling general population.
488 citations
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TL;DR: In this article, the role of infrastructure in a bilateral trade model with transport costs is examined and it is shown that for pairs of countries for which investment in infrastructure is optimal, the model predicts a positive relationship between the level of infrastructure and the volume of trade.
487 citations
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11 Nov 1994TL;DR: Doing Counselling Research Reading the literature Placing Research in Context The Research Process Stages, Tasks and Traps Using Quantitative Methods Test, Rating Scales and Survey Questionnaires Listening to Stories about Therapy From Qualitative Research to Human Science Systematic Inquiry into Individual Cases Does It Work? Evaluating the Outcomes of Counselling Exploring the Interior of Therapy Method and Strategy in Process Research An Ethical Framework for Research Practice Critical Issues in Counselling research as discussed by the authors.
Abstract: Doing Counselling Research Reading the Literature Placing Research in Context The Research Process Stages, Tasks and Traps Using Quantitative Methods Test, Rating Scales and Survey Questionnaires Listening to Stories about Therapy From Qualitative Research to Human Science Systematic Inquiry into Individual Cases Does It Work? Evaluating the Outcomes of Counselling Exploring the Interior of Therapy Method and Strategy in Process Research An Ethical Framework for Research Practice Critical Issues in Counselling Research
485 citations
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TL;DR: This work goes beyond using the technique of activating cells with magnetic nanoparticles as an investigative tool and focuses on its potential to actively control cellular functions and processes with an eye towards biological and clinical applications.
Abstract: By binding magnetic nanoparticles to the surface of cells, it is possible to manipulate and control cell function with an external magnetic field. The technique of activating cells with magnetic nanoparticles offers a means to isolate and explore cellular mechanics and ion channel activation to gain better understanding of these processes. Here, we go beyond using this technique as an investigative tool and focus on its potential to actively control cellular functions and processes with an eye towards biological and clinical applications. In particular, we focus on applications in tissue engineering and regenerative medicine.
485 citations
Authors
Showing all 11402 results
Name | H-index | Papers | Citations |
---|---|---|---|
George Davey Smith | 224 | 2540 | 248373 |
Simon D. M. White | 189 | 795 | 231645 |
James F. Wilson | 146 | 677 | 101883 |
Stephen O'Rahilly | 138 | 520 | 75686 |
Wendy Taylor | 131 | 1252 | 89457 |
Nicola Maffulli | 115 | 1570 | 59548 |
Georg Kresse | 111 | 430 | 244729 |
Patrick B. Hall | 111 | 470 | 68383 |
Peter T. Katzmarzyk | 110 | 618 | 56484 |
John F. Dovidio | 109 | 466 | 46982 |
Elizabeth H. Blackburn | 108 | 344 | 50726 |
Mary L. Phillips | 105 | 422 | 39995 |
Garry P. Nolan | 104 | 474 | 46025 |
Wayne W. Hancock | 103 | 505 | 35694 |
Mohamed H. Sayegh | 103 | 485 | 38540 |