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Institution

Northampton Community College

EducationBethlehem, Pennsylvania, United States
About: Northampton Community College is a education organization based out in Bethlehem, Pennsylvania, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 3410 authors who have published 4582 publications receiving 130398 citations. The organization is also known as: Northampton County Area Community College.


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Journal ArticleDOI
TL;DR: Findings are suggestive of a progressive deterioration of renal function in hypertensive rats exposed to mild maternal protein restriction during fetal life, consistent with the hypothesis that adaptations to maintain renal haemodynamic functions following impairment of fetal nephrogenesis result in an accelerated progression towards glomerulosclerosis and increased intrarenal pressures mediated by rising vascular resistance.
Abstract: Intrauterine growth retardation associated with maternal undernutrition is proposed to play a significant role in the aetiology of hypertension and CHD. Animal experiments suggest that the kidney, which is extremely vulnerable to the adverse effects of growth-retarding factors, may play an important role in the prenatal programming of hypertension. Maintenance of renal haemodynamic functions following structural impairment in fetal life is proposed to require adaptations which raise systemic blood pressure and promote a more rapid progression to renal failure. Rats were fed on diets containing 180 g casein/kg (control) or 90 g casein/kg (low protein) during pregnancy. The offspring were studied in terms of blood pressure, creatinine clearance, blood urea N, plasma and urinary albumin, renal morphometry and metabolic activity at 4, 12 and 20 weeks of age. Blood pressure was elevated at all ages in the low-protein-exposed offspring, relative to control rats. Rats (4 weeks old) exposed to the low-protein diet had smaller kidneys which were shorter and wider than those of control animals. Creatinine clearance was significantly reduced in 4-week-old rats exposed to the low-protein diet. Renal morphometry and creatinine clearance at older ages were not influenced by prenatal diet. Blood urea N, urinary output and urinary albumin excretion were, however, significantly greater in low-protein-exposed rats than in control rats at 20 weeks of age. These findings are suggestive of a progressive deterioration of renal function in hypertensive rats exposed to mild maternal protein restriction during fetal life. This is consistent with the hypothesis that adaptations to maintain renal haemodynamic functions following impairment of fetal nephrogenesis result in an accelerated progression towards glomerulosclerosis and increased intrarenal pressures mediated by rising vascular resistance.

164 citations

Journal ArticleDOI
TL;DR: A policy analysis of food taxes as a way of influencing food consumption and behaviour and there is a case for combining taxes of unhealthy foods with subsidies of healthy foods.
Abstract: Aim: To set out a policy analysis of food taxes as a way of influencing food consumption and behaviour. Design: The study draws on examples of food taxes from the developed world imposed at national and local levels. Studies were identified from a systemised search in six databases with criteria designed to identity articles of policy relevance. Results: The dominant approach identified from the literature was the imposition of food taxes on food to raise general revenue, such as Value Added Tax in the European Union. Food taxes can be applied in various ways, ranging from attempts to directly influence behaviour to those which collect taxes for identified campaigns on healthy eating through to those applied within closed settings such as schools. There is a case for combining taxes of unhealthy foods with subsidies of healthy foods. The evidence from the literature concerning the use and impact of food taxes on food behaviour is not clear and those cases identified are mainly retrospective descriptions of the process. Many food taxes have been withdrawn after short periods of time due to industry lobbying. Conclusions for policy: Small taxes with the clear purpose of promoting the health of key groups, e.g. children, are more likely to receive public support. The focus of many tax initiatives is unclear; although they are generally aimed at consumers, another focus could be food manufacturers, using taxes and subsidies to encourage the production of healthier foods, which could have an effect at a population level. Further consideration needs to be given to this aspect of food taxes. Taxing food (and subsidies) can influence food behaviour within closed systems such as schools and the workplace.

164 citations

Journal ArticleDOI
TL;DR: Pressure perturbation calorimetry is a new technique that measures the heat change in a solution that results when the pressure above the solution is changed, finding that ligand binding to ribonuclease A led to changes in alpha suggesting a burial of some surface area in the ligand-protein complex.

163 citations

Journal ArticleDOI
TL;DR: It is argued that public health nutrition, through the medium of health promotion, needs to address wider issues of who controls the food supply, and thus the influences on the food chain and the food choices of the individual and communities.
Abstract: Food in its many manifestations allows us to explore the global control of health and to examine the ways in which food choice is moulded by many interests. The global food market is controlled by a small number of companies who operate a system that delivers ‘cheap’ food to the countries of the developed world. This ‘cheap’ food comes at a price, which externalises costs to the nation state in terms of health consequences (diabetes, coronary heart disease and other food-related diseases) and to the environment in terms of pollution and the associated clean-up strategies. Food policy has not to any great extent dealt with these issues, opting instead for an approach based on nutrition, food choice and biomedical health. Ignoring wider elements of the food system including issues of ecology and sustainability constrains a broader understanding within public health nutrition. Here we argue that public health nutrition, through the medium of health promotion, needs to address these wider issues of who controls the food supply, and thus the influences on the food chain and the food choices of the individual and communities. Such an upstream approach to food policy (one that has been learned from work on tobacco) is necessary if we are seriously to influence food choice.

162 citations

Journal ArticleDOI
TL;DR: The importance and efficacy of trauma-informed approaches that are sensory supportive, address the individual needs of the person, and strengthen the therapeutic relationship are explored.
Abstract: The national initiative to decrease the use of seclusion and restraint in psychiatric inpatient settings requires innovative methods to facilitate the processes of consumer self-organization, self-care, and positive change. Sensory-based approaches and multisensory rooms are valuable resources as cultures of care shift to become more responsive and collaborative. This article explores the importance and efficacy of trauma-informed approaches that are sensory supportive, address the individual needs of the person, and strengthen the therapeutic relationship.

162 citations


Authors

Showing all 3411 results

NameH-indexPapersCitations
Simon Baron-Cohen172773118071
Pete Smith1562464138819
Martin N. Rossor12867095743
Mark D. Griffiths124123861335
Richard G. Brown8321726205
Brendon Stubbs8175428180
Stuart N. Lane7633715788
Paul W. Burgess6915621038
Thomas Dietz6820337313
Huseyin Sehitoglu6732414378
Susan Golombok6721512856
David S.G. Thomas6322814796
Stephen Morris6344316484
Stephen Robertson6119723363
Michael J. Morgan6026612211
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20233
20221
202182
202073
201968
201865