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Institution

Rutgers University

EducationNew Brunswick, New Jersey, United States
About: Rutgers University is a education organization based out in New Brunswick, New Jersey, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 68736 authors who have published 159418 publications receiving 6713860 citations. The organization is also known as: Rutgers, The State University of New Jersey & Rutgers.


Papers
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Journal ArticleDOI
TL;DR: Recent reorganization of RCSB PDB activities into four integrated, interdependent services is described in detail, together with tools and resources added over the past 2 years to RCSb PDB web portals in support of a ‘Structural View of Biology.’
Abstract: The Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB, rcsb.org), the US data center for the global PDB archive, serves thousands of Data Depositors in the Americas and Oceania and makes 3D macromolecular structure data available at no charge and without usage restrictions to more than 1 million rcsb.org Users worldwide and 600 000 pdb101.rcsb.org education-focused Users around the globe. PDB Data Depositors include structural biologists using macromolecular crystallography, nuclear magnetic resonance spectroscopy and 3D electron microscopy. PDB Data Consumers include researchers, educators and students studying Fundamental Biology, Biomedicine, Biotechnology and Energy. Recent reorganization of RCSB PDB activities into four integrated, interdependent services is described in detail, together with tools and resources added over the past 2 years to RCSB PDB web portals in support of a 'Structural View of Biology.'

827 citations

Journal ArticleDOI
31 Jul 2003-Nature
TL;DR: Here it is found that the spike times of hippocampal pyramidal cells can be predicted more accurately by using the Spike times of simultaneously recorded neurons in addition to the animals location in space, suggesting that cell assemblies are synchronized at this timescale.
Abstract: Neurons can produce action potentials with high temporal precision. A fundamental issue is whether, and how, this capability is used in information processing. According to the 'cell assembly' hypothesis, transient synchrony of anatomically distributed groups of neurons underlies processing of both external sensory input and internal cognitive mechanisms. Accordingly, neuron populations should be arranged into groups whose synchrony exceeds that predicted by common modulation by sensory input. Here we find that the spike times of hippocampal pyramidal cells can be predicted more accurately by using the spike times of simultaneously recorded neurons in addition to the animals location in space. This improvement remained when the spatial prediction was refined with a spatially dependent theta phase modulation. The time window in which spike times are best predicted from simultaneous peer activity is 10-30 ms, suggesting that cell assemblies are synchronized at this timescale. Because this temporal window matches the membrane time constant of pyramidal neurons, the period of the hippocampal gamma oscillation and the time window for synaptic plasticity, we propose that cooperative activity at this timescale is optimal for information transmission and storage in cortical circuits.

826 citations

Journal ArticleDOI
TL;DR: Adenosine, a purine nucleoside that is elaborated at injured and inflamed sites, has a central role in the regulation of inflammatory responses and in limiting inflammatory tissue destruction.

825 citations

Journal ArticleDOI
01 Sep 2003
TL;DR: Traditional relevance feedback methods require that users explicitly give feedback by specifying keywords, selecting and marking documents, or answering questions about their interests, which can be difficult to collect the necessary data and the effectiveness of explicit techniques can be limited.
Abstract: Relevance feedback has a history in information retrieval that dates back well over thirty years (c.f [SL96]). Relevance feedback is typically used for query expansion during short-term modeling of a user's immediate information need and for user profiling during long-term modeling of a user's persistent interests and preferences. Traditional relevance feedback methods require that users explicitly give feedback by, for example, specifying keywords, selecting and marking documents, or answering questions about their interests . Such relevance feedback methods force users to engage in additional activities beyond their normal searching behavior . Since the cost to the user is high and the benefits are not always apparent, it can be difficult to collect the necessary data and the effectiveness of explicit techniques can be limited.

825 citations

Journal ArticleDOI
TL;DR: The history, future, scientific background and regulatory issues related to botanical therapeutics, including plant-derived pharmaceuticals, multicomponent botanical drugs, dietary supplements, functional foods and plant-produced recombinant proteins are discussed.

824 citations


Authors

Showing all 69437 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Daniel Levy212933194778
Eugene V. Koonin1991063175111
Eric Boerwinkle1831321170971
David L. Kaplan1771944146082
Derek R. Lovley16858295315
Mark Gerstein168751149578
Gang Chen1673372149819
Hongfang Liu1662356156290
Robert Stone1601756167901
Mark E. Cooper1581463124887
Michael B. Sporn15755994605
Cumrun Vafa15750988515
Wolfgang Wagner1562342123391
David M. Sabatini155413135833
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023274
20221,029
20218,252
20208,150
20197,398
20186,594