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Institution

Rutgers University

EducationNew Brunswick, New Jersey, United States
About: Rutgers University is a education organization based out in New Brunswick, New Jersey, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 68736 authors who have published 159418 publications receiving 6713860 citations. The organization is also known as: Rutgers, The State University of New Jersey & Rutgers.


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Book
Michael Lewis1
22 Jan 1992
TL;DR: Shame is normal, not pathological, though opposite reactions to shame underlie many conflicts among individuals and groups, and some styles of handling shame are clearly maladaptive.
Abstract: Shame, the quintessential human emotion, received little attention during the years in which the central forces believed to be motivating us were identified as primitive instincts like sex and aggression. Now, redressing the balance, there is an explosion of interest in the self-conscious emotion. Much of our psychic lives involve the negotiation of shame, asserts Michael Lewis, internationally known developmental and clinical psychologist. Shame is normal, not pathological, though opposite reactions to shame underlie many conflicts among individuals and groups, and some styles of handling shame are clearly maladaptive. Illustrating his argument with examples from everyday life, Lewis draws on his own pathbreaking studies and the theory and research of many others to construct the first comprehensive and empirically based account of emotional development focused on shame. In this paperback edition, Michael Lewis adds a compelling new chapter on stigma in which he details the process in which stigmatization produces shame.

954 citations

Journal ArticleDOI
TL;DR: In this article, the authors discuss aspects of global and gauged symmetries in quantum field theory and quantum gravity, focusing on discrete gauge symmetsries, and show that all continuous and continuous gauge symmetry are compact and all charges allowed by Dirac quantization are present in the spectrum.
Abstract: We discuss aspects of global and gauged symmetries in quantum field theory and quantum gravity, focusing on discrete gauge symmetries. An effective Lagrangian description of Zp gauge theories shows that they are associated with an emergent Zp one-form (KalbRamond) gauge symmetry. This understanding leads us to uncover new observables and new phenomena in nonlinear σ-models. It also allows us to expand on Polchinski’s classification of cosmic strings. We argue that in models of quantum gravity, there are no global symmetries, all continuous gauge symmetries are compact, and all charges allowed by Dirac quantization are present in the spectrum. These conjectures are not new, but we present them from a streamlined and unified perspective. Finally, our discussion about string charges and symmetries leads to a more physical and more complete understanding of recently found consistency conditions of supergravity.

953 citations

Journal ArticleDOI
TL;DR: This Review provides a comprehensive overview of the basic biology supporting oncolytic viruses as cancer therapeutic agents, describes oncoleytic viruses in advanced clinical trials and discusses the unique challenges in the development of on colytic virus as a new class of drugs for the treatment of cancer.
Abstract: Oncolytic viruses can kill tumour cells through a dual mechanism of action; the direct lysis of cells, and the induction of an immune response. The first oncolytic virus has been approved in China, and another has been recommended for approval in the United States. This Review discusses the biology of oncolytic viruses as well as key oncolytic viruses in clinical development, and investigates the challenges associated with developing oncolytic viruses as a new therapeutic modality for cancer.

952 citations

Journal ArticleDOI
16 May 2008-Science
TL;DR: Although ∼10% of the ocean's drawdown of atmospheric anthropogenic carbon dioxide may result from this atmospheric nitrogen fertilization, leading to a decrease in radiative forcing, up to about two-thirds of this amount may be offset by the increase in N2O emissions.
Abstract: Increasing quantities of atmospheric anthropogenic fixed nitrogen entering the open ocean could account for up to about a third of the ocean's external (nonrecycled) nitrogen supply and up to 3% of the annual new marine biological production, 0.3 petagram of carbon per year. This input could account for the production of up to 1.6 teragrams of nitrous oxide (N2O) per year. Although 10% of the ocean's drawdown of atmospheric anthropogenic carbon dioxide may result from this atmospheric nitrogen fertilization, leading to a decrease in radiative forcing, up to about two-thirds of this amount may be offset by the increase in N2O emissions. The effects of increasing atmospheric nitrogen deposition are expected to continue to grow in the future.

951 citations

Journal ArticleDOI
TL;DR: In this paper, the authors present evidence supporting the hypothesis that a basic temporal processing impairment in language-impaired children underlies their inability to integrate sensory information that converges in rapid succession in the central nervous system.
Abstract: In this paper we present evidence supporting the hypothesis that a basic temporal processing impairment in language-impaired children underlies their inability to integrate sensory information that converges in rapid succession in the central nervous system. We provide data showing that this deficit is pansensory; that is, affects processing in multiple sensory modalities, and also affects motor output within the millisecond time frame. We also provide data that links these basic temporal integration deficits to specific patterns of speech perception and speech production deficits in language-impaired children. We suggest that these basic temporal deficits cause a cascade of effects starting with disruption of the normal development of an otherwise effective and efficient phonological system. We propose further that these phonological processing deficits result in subsequent failure to learn to speak and to read normally. That is, both the language and reading problems have their basis in deficiently esta...

951 citations


Authors

Showing all 69437 results

NameH-indexPapersCitations
Salim Yusuf2311439252912
Daniel Levy212933194778
Eugene V. Koonin1991063175111
Eric Boerwinkle1831321170971
David L. Kaplan1771944146082
Derek R. Lovley16858295315
Mark Gerstein168751149578
Gang Chen1673372149819
Hongfang Liu1662356156290
Robert Stone1601756167901
Mark E. Cooper1581463124887
Michael B. Sporn15755994605
Cumrun Vafa15750988515
Wolfgang Wagner1562342123391
David M. Sabatini155413135833
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023274
20221,029
20218,252
20208,150
20197,398
20186,594