Rutgers University

About: Rutgers University is a education organization based out in New Brunswick, New Jersey, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 68736 authors who have published 159418 publications receiving 6713860 citations. The organization is also known as: Rutgers, The State University of New Jersey & Rutgers.

Board of Director Diversity and Firm Financial Performance

Abstract: This study examines the relationship between demographic diversity on boards of directors with firm financial performance. This relationship is examined using 1993 and 1998 financial performance data (return on asset and investment) and the percentage of women and minorities on boards of directors for 127 large US companies. Correlation and regression analyses indicate board diversity is positively associated with these financial indicators of firm performance. Implications for both strategic human resource management and future research are discussed.

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

Abstract: Doxorubicin is believed to cause dose-dependent cardiotoxicity through redox cycling and the generation of reactive oxygen species (ROS). Here we show that cardiomyocyte-specific deletion of Top2b (encoding topoisomerase-IIβ) protects cardiomyocytes from doxorubicin-induced DNA double-strand breaks and transcriptome changes that are responsible for defective mitochondrial biogenesis and ROS formation. Furthermore, cardiomyocyte-specific deletion of Top2b protects mice from the development of doxorubicin-induced progressive heart failure, suggesting that doxorubicin-induced cardiotoxicity is mediated by topoisomerase-IIβ in cardiomyocytes.

Percolative phase separation underlies colossal magnetoresistance in mixed-valent manganites

Abstract: Colossal magnetoresistance1—an unusually large change of resistivity observed in certain materials following application of magnetic field—has been extensively researched in ferromagnetic perovskite manganites. But it remains unclear why the magnetoresistive response increases dramatically when the Curie temperature (T C) is reduced. In these materials, T C varies sensitively with changing chemical pressure; this can be achieved by introducing trivalent rare-earth ions of differing size into the perovskite structure2,3,4, without affecting the valency of the Mn ions. The chemical pressure modifies local structural parameters such as the Mn–O bond distance and Mn–O–Mn bond angle, which directly influence the case of electron hopping between Mn ions (that is, the electronic bandwidth). But these effects cannot satisfactorily explain the dependence of magnetoresistance on T C. Here we demonstrate, using electron microscopy data, that the prototypical (La,Pr,Ca)MnO3 system is electronically phase-separated into a sub-micrometre-scale mixture of insulating regions (with a particular type of charge-ordering) and metallic, ferromagnetic domains. We find that the colossal magnetoresistive effect in low-T C systems can be explained by percolative transport through the ferromagnetic domains; this depends sensitively on the relative spin orientation of adjacent ferromagnetic domains which can be controlled by applied magnetic fields.

Efficient power control via pricing in wireless data networks

Abstract: A major challenge in the operation of wireless communications systems is the efficient use of radio resources. One important component of radio resource management is power control, which has been studied extensively in the context of voice communications. With the increasing demand for wireless data services, it is necessary to establish power control algorithms for information sources other than voice. We present a power control solution for wireless data in the analytical setting of a game theoretic framework. In this context, the quality of service (QoS) a wireless terminal receives is referred to as the utility and distributed power control is a noncooperative power control game where users maximize their utility. The outcome of the game results in a Nash (1951) equilibrium that is inefficient. We introduce pricing of transmit powers in order to obtain Pareto improvement of the noncooperative power control game, i.e., to obtain improvements in user utilities relative to the case with no pricing. Specifically, we consider a pricing function that is a linear function of the transmit power. The simplicity of the pricing function allows a distributed implementation where the price can be broadcast by the base station to all the terminals. We see that pricing is especially helpful in a heavily loaded system.