Institution
University of Kentucky
Education•Lexington, Kentucky, United States•
About: University of Kentucky is a education organization based out in Lexington, Kentucky, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 43933 authors who have published 92195 publications receiving 3256087 citations. The organization is also known as: UK.
Topics: Population, Poison control, Health care, Gene, Cancer
Papers published on a yearly basis
Papers
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TL;DR: It is suggested that oxidative stress-induced injury may involve the selective modification of different intracellular proteins, including key enzymes and structural proteins, which precedes and may lead to the neurofibrillary degeneration of neurons in the Alzheimer's disease brain.
492 citations
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TL;DR: It is shown that the Bruton’s tyrosine kinase PH domain binds to PtdIns-3,4,5-P3 with higher affinity than to PtsdIns-4, 5-P2, Ptdins- 3,4-4-P1 or inositol 1,3, 4-5-tetrakisphosphate (Ins-1, 3, 4,5 -P4).
491 citations
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TL;DR: The evolutionary events that gave rise to the tracheophytes are examined, followed by analysis of the genetic and hormonal networks that cooperate to orchestrate vascular development in the gymnosperms and angiosperms, in a comprehensive picture of the state-of-the-art in the area of plant vascular biology.
Abstract: The emergence of the tracheophyte-based vascular system of land plants had major impacts on the evolution of terrestrial biology, in general, through its role in facilitating the development of plants with increased stature, photosynthetic output, and ability to colonize a greatly expanded range of environmental habitats. Recently, considerable progress has been made in terms of our understanding of the developmental and physiological programs involved in the formation and function of the plant vascular system. In this review, we first examine the evolutionary events that gave rise to the tracheophytes, followed by analysis of the genetic and hormonal networks that cooperate to orchestrate vascular development in the gymnosperms and angiosperms. The two essential functions performed by the vascular system, namely the delivery of resources (water, essential mineral nutrients, sugars and amino acids) to the various plant organs and provision of mechanical support are next discussed. Here, we focus on critical questions relating to structural and physiological properties controlling the delivery of material through the xylem and phloem. Recent discoveries into the role of the vascular system as an effective long-distance communication system are next assessed in terms of the coordination of developmental, physiological and defense-related processes, at the whole-plant level. A concerted effort has been made to integrate all these new findings into a comprehensive picture of the state-of-the-art in the area of plant vascular biology. Finally, areas important for future research are highlighted in terms of their likely contribution both to basic knowledge and applications to primary industry.
491 citations
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TL;DR: In this article, a mixture of poly(propylene) and multi-wall carbon nanotubes (up to 2 vol.-%) was melt blended, yielding a good dispersion of nanotsubes without using any organic treatment or additional additives.
Abstract: Nanocomposites based on poly(propylene) and multi-wall carbon nanotubes (up to 2 vol.-%) were melt blended, yielding a good dispersion of nanotubes without using any organic treatment or additional additives. Carbon nanotubes are found to significantly enhance the thermal stability of poly(propylene) in nitrogen at high temperatures. Specifically, the nanotube additive greatly reduced the heat release rate of poly(propylene). They are found to be at least as effective a flame-retardant as clay/poly(propylene) nanocomposites.
491 citations
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Alzheimer's Association1, National Institutes of Health2, Wake Forest University3, University of North Carolina at Chapel Hill4, Harvard University5, Mayo Clinic6, Cleveland Clinic7, University of Washington8, Cornell University9, Rush University Medical Center10, University of British Columbia11, University of Kentucky12, Washington University in St. Louis13, University of Southern California14
TL;DR: A summary of the meeting and the resultant discussion of how vascular factors contribute to Alzheimer's disease and related dementia is summarized, including an outline of next steps needed to move this area of research forward.
Abstract: Scientific evidence continues to demonstrate the linkage of vascular contributions to cognitive impairment and dementia such as Alzheimer's disease. In December, 2013, the Alzheimer's Association, with scientific input from the National Institute of Neurological Disorders and Stroke and the National Heart, Lung and Blood Institute from the National Institutes of Health, convened scientific experts to discuss the research gaps in our understanding of how vascular factors contribute to Alzheimer's disease and related dementia. This manuscript summarizes the meeting and the resultant discussion, including an outline of next steps needed to move this area of research forward.
490 citations
Authors
Showing all 44305 results
Name | H-index | Papers | Citations |
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Mark P. Mattson | 200 | 980 | 138033 |
Carlo M. Croce | 198 | 1135 | 189007 |
Charles A. Dinarello | 190 | 1058 | 139668 |
Richard A. Gibbs | 172 | 889 | 249708 |
Gang Chen | 167 | 3372 | 149819 |
David A. Bennett | 167 | 1142 | 109844 |
Carl W. Cotman | 165 | 809 | 105323 |
Rodney S. Ruoff | 164 | 666 | 194902 |
David Tilman | 158 | 340 | 149473 |
David Cella | 156 | 1258 | 106402 |
Richard E. Smalley | 153 | 494 | 111117 |
Deepak L. Bhatt | 149 | 1973 | 114652 |
Kevin Murphy | 146 | 728 | 120475 |
Jian Yang | 142 | 1818 | 111166 |
Thomas J. Smith | 140 | 1775 | 113919 |