Chromatin dynamics during spermiogenesis.
TLDR
This review highlights the current knowledge on post-meiotic chromatin reorganization and reveals for the first time intriguing parallels in this process in Drosophila and mammals and illustrates the possible mechanisms that lead from a histone-based chromatin to a mainly protamine-based structure during spermatid differentiation.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 2014-03-01 and is currently open access. It has received 411 citations till now. The article focuses on the topics: Histone code & Chromatin.read more
Citations
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Environmentally induced epigenetic transgenerational inheritance of disease.
TL;DR: Observations suggest environmentally induced epigenetic transgenerational inheritance of disease is a critical aspect of disease etiology, toxicology and evolution that needs to be considered.
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The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins.
TL;DR: An overview of the basic roles of BET proteins is presented and the pathological functions of BET and the recent developments in cancer therapy targeting BET proteins in animal models are highlighted.
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Measuring sperm DNA fragmentation and clinical outcomes of medically assisted reproduction: A systematic review and meta analysis
M. Cissen,Madelon van Wely,I. Scholten,Steven A. Mansell,Jan Bruin,Ben W.J. Mol,Didi D.M. Braat,Sjoerd Repping,Geert Hamer +8 more
TL;DR: There is insufficient evidence to recommend the routine use of sperm DNA fragmentation tests in couples undergoing MAR both for the prediction of pregnancy and for the choice of treatment, according to a systematic review and meta-analysis.
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MicroRNAs and spermatogenesis.
TL;DR: The current findings that support the central role of miRNAs in the regulation of spermatogenesis and male fertility are discussed.
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Epigenetic regulation of the histone-to-protamine transition during spermiogenesis.
Jianqiang Bao,Mark T. Bedford +1 more
TL;DR: Recent advances in the understanding of how epigenetic players, such as histone variants and histone writers/readers/erasers, rewire the haploid spermatid genome to facilitate histone substitution by protamines in mammals are discussed.
References
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Maternal control of pattern formation in Xenopus laevis.
Jody A. White,Janet Heasman +1 more
TL;DR: The essential role of maternal factors in pattern formation for Xenopus laevis, focusing on VegT, Vg1, and Wnt11 is reviewed, with results from loss of function experiments demonstrating a clear requirement for these genes in germ layer specification, dorsal-ventral axis formation, and convergence extension.
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Association of NASP with HSP90 in mouse spermatogenic cells: stimulation of ATPase activity and transport of linker histones into nuclei.
TL;DR: Richardson et al. as mentioned in this paper used a cross-linker, 3,3′-dithiobissulfosuccinimidyl propionate, and mass spectrometry to identify a testis/embryo form of NASP (tNASP)-binding partner.
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Meiotic synthesis of testis histones in the rat.
TL;DR: The results prove that the synthesis of several histones during the meiotic prophase is not dependent upon concurrent S-phase DNA synthesis.
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Differential expression of the murine histone genes H3.3A and H3.3B
TL;DR: The histone family of proteins is subdivided into two major groups: the main type histones, which are synthesized in coordination with DNA replication during the S-phase of the cell cycle, and the replacement histone variants, which can be synthesised in the absence of DNA replication substituting maintype histone isoforms.