Chromatin dynamics during spermiogenesis.
TLDR
This review highlights the current knowledge on post-meiotic chromatin reorganization and reveals for the first time intriguing parallels in this process in Drosophila and mammals and illustrates the possible mechanisms that lead from a histone-based chromatin to a mainly protamine-based structure during spermatid differentiation.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 2014-03-01 and is currently open access. It has received 411 citations till now. The article focuses on the topics: Histone code & Chromatin.read more
Citations
More filters
Journal ArticleDOI
RNA from a simple-tandem repeat is required for sperm maturation and male fertility in Drosophila melanogaster.
Wilbur Kyle Mills,Wilbur Kyle Mills,Yuh Chwen G. Lee,Yuh Chwen G. Lee,Yuh Chwen G. Lee,Antje M. Kochendoerfer,Elaine M. Dunleavy,Gary H. Karpen +7 more
TL;DR: Comparisons between closely related Drosophila species suggest that satellites and their transcription evolve quickly to generate new functions, and finding AAGAG transcripts are necessary for male fertility is striking.
Journal ArticleDOI
Reorganized 3D Genome Structures Support Transcriptional Regulation in Mouse Spermatogenesis.
Zhengyu Luo,X Wang,Hong Jiang,Ruoyu Wang,Ruoyu Wang,Ruoyu Wang,Jian Chen,Yusheng Chen,Yusheng Chen,Qianlan Xu,Jun Cao,Xiaowen Gong,Ji Wu,Yun-Gui Yang,Yun-Gui Yang,Wenbo Li,Wenbo Li,Chunsheng Han,C. Yan Cheng,Michael G. Rosenfeld,Fei Sun,Xiaoyuan Song +21 more
TL;DR: This work showed that the switching of A/B compartments between spermatogenic stages is tightly associated with meiosis-specific mRNAs and piRNAs expression and indicated that chromatin accessibility per se is not responsible for the TAD and loop diminishment at pachytene.
Journal ArticleDOI
Estrogen, through estrogen receptor 1, regulates histone modifications and chromatin remodeling during spermatogenesis in adult rats.
TL;DR: The activating and repressing histone marks in spermatozoa, which play a critical role in early embryo development, were deregulated after both the ESR agonist treatments, highlighting the importance of ESRs in regulating different epigenetic processes during spermatogenesis, which are crucial for male fertility.
Journal ArticleDOI
Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution.
Matthew P. Davis,Claudia Carrieri,Harpreet K Saini,Stijn van Dongen,Tommaso Leonardi,Giovanni Bussotti,Giovanni Bussotti,Jack M. Monahan,Tania Auchynnikava,Angelo Bitetti,Juri Rappsilber,Juri Rappsilber,Robin C. Allshire,Alena Shkumatava,Dónal O'Carroll,Anton J. Enright +15 more
TL;DR: It is demonstrated that LTRs can act as tissue‐specific promoters and contribute to post‐mitotic spermatogenic transcriptome diversity and the proposed transposon promoters are a mechanism by which the genome can explore novel transcriptional substrates, increasing evolutionary plasticity and allowing for the genesis of novel coding and non‐coding genes.
Journal ArticleDOI
Redox reactions in mammalian spermatogenesis and the potential targets of reactive oxygen species under oxidative stress.
Junichi Fujii,Hirotaka Imai +1 more
TL;DR: Sulfoxidation of chromatin is a unique process in sperm maturation, and GPX4 has emerged as a promising enzyme that plays essential roles in the production of fertile sperm, but the involvement of other redox proteins is also becoming evident.
References
More filters
Journal ArticleDOI
The language of covalent histone modifications.
Brian D. Strahl,C D Allis +1 more
TL;DR: It is proposed that distinct histone modifications, on one or more tails, act sequentially or in combination to form a ‘histone code’ that is, read by other proteins to bring about distinct downstream events.
Journal ArticleDOI
Proteasome inhibitors: valuable new tools for cell biologists.
Do Hee Lee,Alfred L. Goldberg +1 more
TL;DR: The actions of selective proteasome inhibitors are described, how they can be used to investigate cellular responses, the functions of the proteasomes demonstrated by such studies and their potential applications in the future.
Journal ArticleDOI
Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification
Minjia Tan,Hao Luo,Sangkyu Lee,Fulai Jin,Jeong Soo Yang,Emilie Montellier,Thierry Buchou,Zhongyi Cheng,Sophie Rousseaux,Nisha Rajagopal,Zhike Lu,Zhen Ye,Qin Zhu,Joanna Wysocka,Yang Ye,Saadi Khochbin,Bing Ren,Yingming Zhao +17 more
TL;DR: The identification of 67 previously undescribed histone modifications is reported, increasing the current number of known histone marks by about 70%, and lysine crotonylation (Kcr) is investigated, confirming that it represents an evolutionarily-conserved histone posttranslational modification.
Book
comprehensive molecular insect science
TL;DR: Includes: Molecular Genetics of Insect Fertilization Sex Determination and the Development of the Genital Disc Dosage Compensation Fat-Cell Development The Juvenile Hormones.