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Journal ArticleDOI

Complete Dna-Sequence Of Yeast Chromosome-Xi

Bernard Dujon, +112 more
- 02 Jun 1994 - 
- Vol. 369, Iss: 6479, pp 371-378
TLDR
The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined, and the 666,448-base-pair sequence has revealed general chromosome patterns.
Abstract
The complete DNA sequence of the yeast Saccharomyces cerevisiae chromosome XI has been determined. In addition to a compact arrangement of potential protein coding sequences, the 666,448-base-pair sequence has revealed general chromosome patterns; in particular, alternating regional variations in average base composition correlate with variations in local gene density along the chromosome. Significant discrepancies with the previously published genetic map demonstrate the need for using independent physical mapping criteria.

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Citations
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Journal ArticleDOI

New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

TL;DR: A dominant resistance module, for selection of S. cerevisiae transformants, which entirely consists of heterologous DNA is constructed and tested, and some kanMX modules are flanked by 470 bp direct repeats, promoting in vivo excision with frequencies of 10–3–10–4.
Journal ArticleDOI

Sequencing and comparison of yeast species to identify genes and regulatory elements

TL;DR: A comparative analysis of the yeast Saccharomyces cerevisiae based on high-quality draft sequences of three related species, which inferred a putative function for most of these motifs, and provided insights into their combinatorial interactions.
Journal ArticleDOI

The genome sequence of the filamentous fungus Neurospora crassa

James E. Galagan, +77 more
- 24 Apr 2003 - 
TL;DR: A high-quality draft sequence of the N. crassa genome is reported, suggesting that RIP has had a profound impact on genome evolution, greatly slowing the creation of new genes through genomic duplication and resulting in a genome with an unusually low proportion of closely related genes.
Journal ArticleDOI

Common Principles of Protein Translocation Across Membranes

TL;DR: Most major systems that transport proteins across a membrane share the following features: an amino-terminal transient signal sequence on the transported protein, a targeting system on the cis side of the membrane, a hetero-oligomeric transmembrane channel, a peripherally attached protein translocation motor that is powered by the hydrolysis of nucleoside triphosphate.
Proceedings ArticleDOI

A new Voronoi-based surface reconstruction algorithm

TL;DR: The algorthim is the first for this problem with provable guarantees for the reconstruction of surfaces from unorganized sample points in IR3, based on the three-dimensional Voronoi diagram.
References
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Journal ArticleDOI

The codon Adaptation Index--a measure of directional synonymous codon usage bias, and its potential applications.

TL;DR: A simple, effective measure of synonymous codon usage bias, the Codon Adaptation Index, is detailed, useful for predicting the level of expression of a gene, for assessing the adaptation of viral genes to their hosts, and for making comparisons ofCodon usage in different organisms.
Journal ArticleDOI

Fluorescence detection in automated DNA sequence analysis

TL;DR: A method for the partial automation of DNA sequence analysis by means of a fluorophore covalently attached to the oligonucleotide primer used in enzymaticDNA sequence analysis.
Journal ArticleDOI

Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

TL;DR: The results suggest that 3-phosphorylated phosphoinositides, whose physiological significance has not been determined, are an important signal in cell cycle activation in yeast and may act in a signalTransduction pathway similar to the interleukin-2 signal transduction pathway in T cells.
Journal ArticleDOI

The complete DNA sequence of yeast chromosome III.

Stephen G. Oliver, +146 more
- 07 May 1992 - 
TL;DR: The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined, which is the first complete sequence analysis of an entire chromosome from any organism.
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