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Open AccessJournal ArticleDOI

Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

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TLDR
The metagenomically characterized the murine and human mucosal-associated gastrointestinal microbiome and found it to only partially correlate with stool microbiome, indicating that empiric probiotics supplementation may be limited in universally and persistently impacting the gut mucosa.
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This article is published in Cell.The article was published on 2018-09-06 and is currently open access. It has received 900 citations till now. The article focuses on the topics: Gastrointestinal Microbiome & Microbiome.

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Book ChapterDOI

Gut Microbiome, Diabetes, and Obesity: Complex Interplay of Physiology

TL;DR: Evidence is gathered to shed light on the complicated interrelations of gut microbiome, diabetes, and obesity, assessing the current literature and suggesting novel concepts and methodologies for future studies.
Journal ArticleDOI

The structure design and application of oxidized polysaccharides delivery systems for controlled uptake and release of food functional ingredients

TL;DR: In this paper , a review of the development of targeted and responsive oxidized polysaccharides (OP)-based delivery systems is presented and the behavior of absorption and release of functional ingredients in OP-based carriers is discussed.
Posted ContentDOI

Relationship between faecal microbiota and plasma metabolome in rats fed NK603 and MON810 GM maize from the GMO90+ study

TL;DR: It is shown that the consumption of the widely cultivated GM maize varieties NK603 and MON810 even up to 33% of the total diet had no effect on the status of the faecal microbiota compared to non-GM near isogenic lines.
Journal ArticleDOI

Enriching captivity conditions with natural elements does not prevent the loss of wild‐like gut microbiota but shapes its compositional variation in two small mammals

TL;DR: The results of this experiment do not support the use of microbially enriched environments to retain wild‐like microbial diversities and compositions, yet show that specific housing conditions can significantly affect the drift of microbial communities under captivity.
Journal ArticleDOI

Predictive and Preventive Mucosal Communications in Particulate Matter Exposure-Linked Renal Distress

TL;DR: In this paper, the impact of particulate matter exposure on the mucosal barrier and the vicious feedback cycle in the mucosal environment was investigated, and the authors found that PM-induced alteration of the mucosa barrier integrity, the microbial community has a pivotal role in the xenobiotic metabolism and individual susceptibility to PM toxicity, and that the progress of mucosa-associated renal disease is counteracted by endogenous protective responses.
References
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Journal ArticleDOI

Trimmomatic: a flexible trimmer for Illumina sequence data

TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
Journal ArticleDOI

Fast gapped-read alignment with Bowtie 2

TL;DR: Bowtie 2 combines the strengths of the full-text minute index with the flexibility and speed of hardware-accelerated dynamic programming algorithms to achieve a combination of high speed, sensitivity and accuracy.
Journal ArticleDOI

KEGG: Kyoto Encyclopedia of Genes and Genomes

TL;DR: The Kyoto Encyclopedia of Genes and Genomes (KEGG) as discussed by the authors is a knowledge base for systematic analysis of gene functions in terms of the networks of genes and molecules.
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Trending Questions (1)
What are the best probiotics for colonization resistance?

The study suggests that probiotics have a person-specific impact on gut mucosal colonization, indicating the need for personalized probiotic approaches.