Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features
Niv Zmora,Niv Zmora,Gili Zilberman-Schapira,Jotham Suez,Uria Mor,Mally Dori-Bachash,Stavros Bashiardes,Eran Kotler,Maya Zur,Dana Regev-Lehavi,Rotem Ben-Zeev Brik,Sara Federici,Yotam Cohen,Raquel Linevsky,Daphna Rothschild,Andreas E. Moor,Shani Ben-Moshe,Alon Harmelin,Shalev Itzkovitz,Nitsan Maharshak,Nitsan Maharshak,Oren Shibolet,Oren Shibolet,Hagit Shapiro,Meirav Pevsner-Fischer,Itai Sharon,Zamir Halpern,Zamir Halpern,Eran Segal,Eran Elinav +29 more
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TLDR
The metagenomically characterized the murine and human mucosal-associated gastrointestinal microbiome and found it to only partially correlate with stool microbiome, indicating that empiric probiotics supplementation may be limited in universally and persistently impacting the gut mucosa.About:
This article is published in Cell.The article was published on 2018-09-06 and is currently open access. It has received 900 citations till now. The article focuses on the topics: Gastrointestinal Microbiome & Microbiome.read more
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Engineering the microbiome for animal health and conservation
Se Jin Song,Douglas C. Woodhams,Douglas C. Woodhams,Cameron Martino,Celeste Allaband,Andre Mu,Sandrine Javorschi-Miller-Montgomery,Jan S. Suchodolski,Rob Knight +8 more
TL;DR: The rapid progress currently being made in human medicine and the examples to date of application of probiotics and other microbiome-directed therapies in taxa ranging from horses to salamanders to bees suggest excellent prospects for these technologies as they are further developed.
Journal ArticleDOI
Quantifying spatiotemporal variability and noise in absolute microbiota abundances using replicate sampling.
Brian W. Ji,Ravi U. Sheth,Purushottam D. Dixit,Yiming Huang,Andrew Kaufman,Harris H. Wang,Dennis Vitkup +6 more
TL;DR: This work applied DIVERS to investigate a high-resolution time series of the human gut microbiome and a spatial survey of a soil bacterial community in Manhattan’s Central Park, revealing substantial spatial heterogeneity of gut microbiota, and high temporal covariances of taxa within the Bacteroidetes phylum.
Journal ArticleDOI
The human gut microbiome and health inequities.
Katherine R. Amato,Marie-Claire Arrieta,Meghan B. Azad,Meghan B. Azad,Michael T. Bailey,Michael T. Bailey,Josiane L. Broussard,Carlijn E Bruggeling,Erika C. Claud,Elizabeth K. Costello,Emily R. Davenport,Bas E. Dutilh,Bas E. Dutilh,Holly A. Swain Ewald,Paul W. Ewald,Erin C. Hanlon,Wrenetha Julion,Ali Keshavarzian,Corinne F. Maurice,Gregory E. Miller,Geoffrey A. Preidis,Laure Ségurel,Burton H. Singer,Sathish Subramanian,Sathish Subramanian,Liping Zhao,Liping Zhao,Christopher W. Kuzawa +27 more
TL;DR: In this article, the authors argue that accounting for host-gut microbe interactions will improve understanding and management of health inequities, and that health policy must begin to consider the microbiome as an important pathway linking environments to population health.
Journal ArticleDOI
Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Abeed H. Chowdhury,Alfred Adiamah,Anisa Kushairi,Krishna K. Varadhan,Zeljko Krznaric,Anil D. Kulkarni,Keith R. Neal,Dileep N. Lobo,Dileep N. Lobo +8 more
TL;DR: Probiotics and synbiotics are safe and effective nutritional adjuncts in reducing postoperative infective complications in elective abdominal surgery and the treatment effects are greatest withsynbiotics.
Journal ArticleDOI
Gut Microbiota as a Therapeutic Target to Ameliorate the Biochemical, Neuroanatomical, and Behavioral Effects of Traumatic Brain Injuries.
TL;DR: The etiological role of the gut microbiome in the biochemical, neuroanatomical, and behavioral/cognitive consequences of TBI is addressed, as well as the potential of gut microbiome manipulation in the form of probiotics as an effective therapeutic to ameliorate TBI-induced pathology and symptoms are explored.
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