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Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features

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TLDR
The metagenomically characterized the murine and human mucosal-associated gastrointestinal microbiome and found it to only partially correlate with stool microbiome, indicating that empiric probiotics supplementation may be limited in universally and persistently impacting the gut mucosa.
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This article is published in Cell.The article was published on 2018-09-06 and is currently open access. It has received 900 citations till now. The article focuses on the topics: Gastrointestinal Microbiome & Microbiome.

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Comparison of the Effects of Enzymolysis Seaweed Powder and Saccharomyces boulardii on Intestinal Health and Microbiota Composition in Kittens

TL;DR: In this article , the effects of dietary supplementation with enzymolysis seaweed powder and Saccharomyces boulardii on the intestinal health of kittens were compared with three treatment groups for a 4-week feeding trial.
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The Long and Winding Road to the Best Clinical Research and Personalized Therapy With Probiotics: Do Not Forget Host Physiology

TL;DR: In this article , the authors suggest several implications for clinicians and researchers using probiotics, including the difficulty in clinical research conducted using a probiotic, the results of previously reported clinical trials with probiotics are heterogeneous, even in the same disease, such as irritable bowel syndrome.
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Why don't probiotics work?

TL;DR: Claims in the field of microbiota-gut-brain research remain problematic without appropriate controls and adequate statistical power, and the field is urged to investigate the complex multipathway interactions between the microbiome and the gut-brain axis.
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Probiotics and Prebiotics: Any Role in Menopause-Related Diseases?

TL;DR: In this paper , the authors provide an overview of the menopause-related changes in microbiota and their role in the pathogenesis of menopausal related diseases (e.g., osteoporosis, breast cancer, endometrial hyperplasia, periodontitis, and cardiometabolic diseases).
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Gut Microbiome in Sepsis.

TL;DR: In this article , an English language literature review was performed to summarize the current knowledge of sepsis-induced gut microbiome dysbiosis and showed that conversion of a normal microbiome to a pathobiome is associated with worsened mortality.
References
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Trimmomatic: a flexible trimmer for Illumina sequence data

TL;DR: Timmomatic is developed as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data and is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested.
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Fast gapped-read alignment with Bowtie 2

TL;DR: Bowtie 2 combines the strengths of the full-text minute index with the flexibility and speed of hardware-accelerated dynamic programming algorithms to achieve a combination of high speed, sensitivity and accuracy.
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KEGG: Kyoto Encyclopedia of Genes and Genomes

TL;DR: The Kyoto Encyclopedia of Genes and Genomes (KEGG) as discussed by the authors is a knowledge base for systematic analysis of gene functions in terms of the networks of genes and molecules.
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What are the best probiotics for colonization resistance?

The study suggests that probiotics have a person-specific impact on gut mucosal colonization, indicating the need for personalized probiotic approaches.