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Journal ArticleDOI

Suicide prevention strategies: a systematic review.

TLDR
Physician education in depression recognition and treatment and restricting access to lethal methods reduce suicide rates, and other interventions need more evidence of efficacy.
Abstract
ContextIn 2002, an estimated 877 000 lives were lost worldwide through suicide. Some developed nations have implemented national suicide prevention plans. Although these plans generally propose multiple interventions, their effectiveness is rarely evaluated.ObjectivesTo examine evidence for the effectiveness of specific suicide-preventive interventions and to make recommendations for future prevention programs and research.Data Sources and Study SelectionRelevant publications were identified via electronic searches of MEDLINE, the Cochrane Library, and PsychINFO databases using multiple search terms related to suicide prevention. Studies, published between 1966 and June 2005, included those that evaluated preventative interventions in major domains; education and awareness for the general public and for professionals; screening tools for at-risk individuals; treatment of psychiatric disorders; restricting access to lethal means; and responsible media reporting of suicide.Data ExtractionData were extracted on primary outcomes of interest: suicidal behavior (completion, attempt, ideation), intermediary or secondary outcomes (treatment seeking, identification of at-risk individuals, antidepressant prescription/use rates, referrals), or both. Experts from 15 countries reviewed all studies. Included articles were those that reported on completed and attempted suicide and suicidal ideation; or, where applicable, intermediate outcomes, including help-seeking behavior, identification of at-risk individuals, entry into treatment, and antidepressant prescription rates. We included 3 major types of studies for which the research question was clearly defined: systematic reviews and meta-analyses (n = 10); quantitative studies, either randomized controlled trials (n = 18) or cohort studies (n = 24); and ecological, or population- based studies (n = 41). Heterogeneity of study populations and methodology did not permit formal meta-analysis; thus, a narrative synthesis is presented.Data SynthesisEducation of physicians and restricting access to lethal means were found to prevent suicide. Other methods including public education, screening programs, and media education need more testing.ConclusionsPhysician education in depression recognition and treatment and restricting access to lethal methods reduce suicide rates. Other interventions need more evidence of efficacy. Ascertaining which components of suicide prevention programs are effective in reducing rates of suicide and suicide attempt is essential in order to optimize use of limited resources.

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Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015

Haidong Wang, +844 more
- 08 Oct 2016 - 
TL;DR: The Global Burden of Disease 2015 Study provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015, finding several countries in sub-Saharan Africa had very large gains in life expectancy, rebounding from an era of exceedingly high loss of life due to HIV/AIDS.
Journal ArticleDOI

Suicide and Suicidal Behavior

TL;DR: Examination of prevalence of, trends in, and risk and protective factors for suicidal behavior in the United States and cross-nationally revealed significant cross-national variability in the prevalence of suicidal behavior but consistency in age of onset, transition probabilities, and key risk factors.
Journal ArticleDOI

Mortality in Mental Disorders and Global Disease Burden Implications: A Systematic Review and Meta-analysis

TL;DR: Estimates suggest that mental disorders rank among the most substantial causes of death worldwide, and efforts to quantify and address the global burden of illness need to better consider the role of mental disorders in preventable mortality.
References
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Journal ArticleDOI

Effect of prophylactic treatment on suicide risk in patients with major affective disorders. Data from a randomized prospective trial.

TL;DR: The findings support the view that lithium has a specific antisuicidal effect over and above its prophylactic benefit.
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Antidepressant medications and the relative risk of suicide attempt and suicide

TL;DR: The higher risk of suicide with tricyclics vs nontricyclics may be explained by a higher rate of death from overdose rather than more suicide attempts, which has important implications for the choice of an antidepressant for the depressed patient at risk for suicidal behavior.
Journal ArticleDOI

Antidepressant treatment and risk of suicide attempt by adolescents with major depressive disorder: a propensity-adjusted retrospective cohort study.

TL;DR: Antidepressant medication use had no statistically significant effect on the likelihood of suicide attempt in a large cohort of adolescents across the US after propensity adjustment for treatment allocation and controlling for other factors.
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The 18-month impact of an emergency room intervention for adolescent female suicide attempters.

TL;DR: The intervention's impact was greatest on maternal emotional distress and family cohesion among SA who were highly symptomatic, and SA's attendance at therapy sessions following the ER visit was significantly associated with only one outcome--family adaptability.
Journal ArticleDOI

Improving adherence to antidepressants: a systematic review of interventions.

TL;DR: Evidence is found to support the introduction of interventions to enhance adherence with antidepressant medication in primary care, not only because of better adherence but alsoBecause collaborative care interventions require additional resources, better understanding of the mode of action of different programs is needed to reduce avoidable costs.
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