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Guy A. Rouleau

Researcher at Montreal Neurological Institute and Hospital

Publications -  935
Citations -  75050

Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.

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Family Study of Restless Legs Syndrome in Quebec, Canada Clinical Characterization of 671 Familial Cases

Lan Xiong, +9 more
- 01 May 2010 - 
TL;DR: The clinical data indicated that fRLS is more prominent among women who also had increased incidence of anemia/iron deficiency, arthritis, and number of pregnancies, and afflicted women tend to have a much younger age of onset.
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Novel RPGR mutations with distinct retinitis pigmentosa phenotypes in French-Canadian families.

Robert K. Koenekoop, +7 more
- 01 Oct 2003 - 
TL;DR: Different RPGR mutations lead to distinct RP phenotypes, with a highly variable inter- and intrafamilial phenotypic spectrum of disease that is associated with the type of mutation in RPGR and nonrandom X chromosome inactivation, respectively.
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Molecular mechanisms underlying polyalanine diseases.

C. Messaed, +1 more
- 01 Jun 2009 - 
TL;DR: An overview of recent advances on the molecular mechanisms underlying the group of polyalanine diseases is presented and insights into the pathological impact ofpolyalanine tract expansion on protein dysfunction are provided.
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Familial meningioma is not allelic to neurofibromatosis 2

Stefan M. Pulst, +4 more
- 01 Oct 1993 - 
TL;DR: Results support the existence of a familial meningioma locus that is distinct from the NF2 locus, and study of a family with multiple meniomas and ependymomas in two generations proves this.
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Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders.

Surya Madabattula, +8 more
- 13 Jun 2015 - 
TL;DR: A sensitized version of the negative geotaxis assay is designed that allows for the detection of milder defects earlier and has the ability to evaluate these defects over time, and is an excellent technique for screening candidate drugs in Drosophila mutants with locomotion defects.