G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
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Lack of Causal Effects or Genetic Correlation between Restless Legs Syndrome and Parkinson's Disease
Mehrdad Asghari Estiar,Mehrdad Asghari Estiar,Konstantin Senkevich,Konstantin Senkevich,Eric Yu,Eric Yu,Parizad Varghaei,Parizad Varghaei,Lynne Krohn,Lynne Krohn,Sara Bandres-Ciga,Alastair J. Noyce,Alastair J. Noyce,Guy A. Rouleau,Guy A. Rouleau,Ziv Gan-Or,Ziv Gan-Or +16 more
TL;DR: In this paper, a two-sample Mendelian randomization (MR) and linkage disequilibrium score regression (LDSC) was performed using summary statistics from recent genome-wide meta-analyses of Parkinson's disease and restless legs syndrome (RLS).
Proceedings ArticleDOI
Evolutionary Design and Experimental Evaluation of Selective Hammerhead Ribozymes
TL;DR: In this paper, an evolutionary algorithm was used for the design of RNA-activated hammerhead ribozymes that selectively cleave a mutant transcript, while leaving the wild type transcript largely unaffected.
Journal ArticleDOI
HLA in isolated REM sleep behavior disorder and Lewy body dementia.
Eric Yu,Lynne Krohn,Jennifer A. Ruskey,Farnaz Asayesh,Dan Spiegelman,Zalak Shah,Ruth Chia,Isabelle Arnulf,Michele T.M. Hu,Jacques Montplaisir,J. F. Gagnon,Alex Desautels,Yves Dauvilliers,Gian Luigi Gigli,Mariarosaria Valente,Francesco Janes,Andrea Bernardini,Birgit Högl,Ambra Stefani,Abubaker Mohamed Ahmed Ibrahim,Anna Heidbreder,Karel Sonka,Petr Dusek,David Kemlink,Wolfgang H. Oertel,Annette Janzen,Giuseppe Plazzi,Elena Antelmi,Michela Figorilli,Monica Puligheddu,Brit Mollenhauer,Claudia Trenkwalder,Friederike Sixel-Döring,Valérie Cochen De Cock,Luigi Ferini-Strambi,Femke Dijkstra,Mineke K. Viaene,B. Abril,Bradley F. Boeve,Guy A. Rouleau,Ronald B. Postuma,Sonja W. Scholz,Ziv Gan-Or +42 more
TL;DR: This paper examined whether the human leukocyte antigen (HLA) locus plays a role in isolated/idiopathic REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD).