G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
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Journal ArticleDOI
A locus for primary lateral sclerosis on chromosome 4ptel-4p16.1.
TL;DR: PLS1 does not map near any other identified loci for upper or lower motor neuron diseases and thus represents a novel locus for PLS.
Posted ContentDOI
Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder
Liping Hou,Sarah E. Bergen,Nirmala Akula,Jie Song,Christina M. Hultman,Mikael Landén,Mazda Adli,Martin Alda,Raffaella Ardau,Bárbara Arias,Jean-Michel Aubry,Lena Backlund,Judith A. Badner,Thomas B. Barrett,Michael Bauer,Bernhard T. Baune,Frank Bellivier,Antonio Benabarre,Susanne Bengesser,Wade H. Berrettini,Abesh Kumar Bhattacharjee,Joanna M. Biernacka,Armin Birner,Cinnamon S. Bloss,Clara Brichant-Petitjean,Elise T. Bui,William Byerley,Pablo Cervantes,Caterina Chillotti,Sven Cichon,Francesc Colom,William Coryell,David Craig,Cristiana Cruceanu,Piotr M. Czerski,Tony Davis,Alexandre Dayer,Franziska Degenhardt,Maria Del Zompo,J. Raymond DePaulo,Howard J. Edenberg,Bruno Etain,Peter Falkai,Tatiana Foroud,Andreas J. Forstner,Louise Frisén,Mark A. Frye,Janice M. Fullerton,Sébastien Gard,Julie Garnham,Elliot S. Gershon,Fernando S. Goes,Tiffany A. Greenwood,Maria Grigoroiu-Serbanescu,Joanna Hauser,Urs Heilbronner,Stefanie Heilmann-Heimbach,Stefan Herms,Stefan Herms,Maria Hipolito,Shashi Hitturlingappa,Per Hoffmann,Andrea Hofmann,Stéphane Jamain,Esther Jiménez,Jean-Pierre Kahn,Layla Kassem,John R. Kelsoe,Sarah Kittel-Schneider,Sebastian Kliwicki,Daniel L. Koller,Barbara König,N. Lackner,Gonzalo Laje,Maren Lang,Catharina Lavebratt,William Lawson,Marion Leboyer,Susan G. Leckband,Chunyu Liu,Anna Maaser,Pamela B. Mahon,Wolfgang Maier,Mario Maj,Mirko Manchia,Lina Martinsson,Michael McCarthy,Susan L. McElroy,Melvin G. McInnis,Rebecca McKinney,Philip B. Mitchell,Marina Mitjans,Francis M. Mondimore,Palmiero Monteleone,Thomas W. Mühleisen,Caroline M. Nievergelt,Markus M. Nöthen,Tomas Novak,John I. Nurnberger,Evaristus A. Nwulia,Urban Ösby,Andrea Pfennig,James B. Potash,Peter Propping,Andreas Reif,Eva Z. Reininghaus,John P. Rice,Marcella Rietschel,Guy A. Rouleau,Janusz K. Rybakowski,Martin Schalling,William A. Scheftner,Peter R. Schofield,Nicholas J. Schork,Thomas G. Schulze,Johannes Schumacher,Barbara W. Schweizer,Giovanni Severino,Tatyana Shekhtman,Paul D. Shilling,Christian Simhandl,Claire Slaney,Erin N. Smith,Alessio Squassina,Thomas Stamm,Pavla Stopkova,Fabian Streit,Jana Strohmaier,Szabolcs Szelinger,Sarah K. Tighe,Alfonso Tortorella,Gustavo Turecki,Eduard Vieta,Julia Volkert,Stephanie H. Witt,Adam Wright,Peter P. Zandi,Peng Zhang,Sebastian Zöllner,Francis J. McMahon +139 more
TL;DR: The results add to a growing list of common autosomal variants involved in BD and illustrate the power of comparing well-characterized cases to an excess of controls in GWAS.
Posted ContentDOI
GBA variants in REM sleep behavior disorder: a multicenter study
Lynne Krohn,Lynne Krohn,Jennifer A. Ruskey,Jennifer A. Ruskey,Uladzislau Rudakou,Uladzislau Rudakou,Etienne Leveille,Farnaz Asayesh,Farnaz Asayesh,Michele T.M. Hu,Isabelle Arnulf,Yves Dauvilliers,Birgit Högl,Ambra Stefani,Christelle Charley Monaca,Abril Beatriz,Giuseppe Plazzi,Elena Antelmi,Luigi Ferini-Strambi,Anna Heidbreder,Bradley F. Boeve,Alberto J. Espay,Valérie Cochen De Cock,Brit Mollenhauer,Friederike Sixel-Döring,Claudia Trenkwalder,Karel Sonka,David Kemlink,Michela Figorilli,Monica Puligheddu,Femke Dijkstra,Mineke Viaene,Wolfgang H. Oertel,Marco Toffoli,Marco Toffoli,Gian Luigi Gigli,Mariarosaria Valente,Jean-François Gagnon,Alex Desautels,Jacques Montplaisir,Ronald B. Postuma,Ronald B. Postuma,Guy A. Rouleau,Guy A. Rouleau,Ziv Gan-Or,Ziv Gan-Or +45 more
TL;DR: GBA variants robustly and differentially increase the risk of iRBD and the rate of conversion to neurodegeneration is also increased and may be faster among severe GBA variant carriers, although confirmation will be required in larger samples.
Journal ArticleDOI
Fine mapping the candidate region for peripheral neuropathy with or without agenesis of the corpus callosum in the French Canadian population
Heidi C Howard,Heidi C Howard,Marie-Pierre Dubé,Marie-Pierre Dubé,Claude Prévost,Jean-Pierre Bouchard,Jean Mathieu,Guy A. Rouleau,Guy A. Rouleau +8 more
TL;DR: Haplotype analysis confirmed the presence of a founder haplotype in the FC population, and identified critical recombinants which reduce the ACCPN candidate interval to a ≈2 cM or 1000 Kb region flanked by markers D15S1040 and ACTC.
Journal ArticleDOI
Is Persistent Motor or Vocal Tic Disorder a Milder Form of Tourette Syndrome
Karla Claudio-Campos,Daniel A. Stevens,Sang-Wahn Koo,Alexa Valko,Oscar J. Bienvenu,Cathy Budman,Danielle C. Cath,Sabrina M. Darrow,Daniel A. Geller,Fernando S. Goes,Marco A. Grados,Benjamin D. Greenberg,Erica Greenberg,Matthew E. Hirschtritt,Cornelia Illmann,Franjo Ivankovic,Robert A. King,James A. Knowles,Janice Krasnow,Paul C. Lee,Gholson J. Lyon,James T. McCracken,Mary M. Robertson,Lisa Osiecki,Mark A. Riddle,Guy A. Rouleau,Paul Sandor,Gerald Nestadt,Jack Samuels,Jeremiah M. Scharf,Carol A. Mathews +30 more
TL;DR: In this article, the authors compared the prevalence and number of comorbid psychiatric disorders, tic severity, age at tic onset, and family history for Tourette syndrome and persistent motor or vocal tic disorder.