G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
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Genome-Wide Association Study of Intracranial Aneurysm Identifies a New Association on Chromosome 7
Tatiana Foroud,Dongbing Lai,Daniel L. Koller,Femke N G van 't Hof,Mitja I. Kurki,Mitja I. Kurki,Mitja I. Kurki,Craig S. Anderson,Robert D. Brown,Edward Sander Connolly,Johan G. Eriksson,Matthew L. Flaherty,Myriam Fornage,Mikael von und zu Fraunberg,Emilia I. Gaal,Aki Laakso,Juha Hernesniemi,John H. Huston,Juha E. Jääskeläinen,Lambertus A. Kiemeney,Riku Kivisaari,Dawn Kleindorfer,Nerissa U. Ko,Hanna Lehto,Jason Mackey,Irene Meissner,Charles J Moomaw,Thomas H. Mosley,Marek Moskała,Mika Niemelä,Aarno Palotie,Aarno Palotie,Aarno Palotie,Joanna Pera,Gabriël J.E. Rinkel,Stephan Ripke,Stephan Ripke,Guy A. Rouleau,Ynte M. Ruigrok,Laura Sauerbeck,Agnieszka Slowik,Sita H. Vermeulen,Daniel Woo,Bradford B. Worrall,Joseph Broderick +44 more
TL;DR: A novel region on chromosome 7 has been previously associated with ischemic stroke and the large vessel stroke occlusive subtype (including HDAC9), suggesting a possible genetic link between this stroke subtype and IA.
Posted ContentDOI
Genome-wide characterization of copy number variants in epilepsy patients
Jean Monlong,Simon Girard,Caroline Meloche,Maxime Cadieux-Dion,Danielle M. Andrade,Ron G. Lafreniere,Micheline Gravel,Dan Spiegelman,Alexandre Dionne-Laporte,Cyrus Boelman,Fadi F. Hamdan,Jacques L. Michaud,Guy A. Rouleau,Berge A. Minassian,Guillaume Bourque,Patrick Cossette +15 more
TL;DR: In this paper, a comprehensive characterization of copy number variants (CNVs) in 198 individuals affected with epilepsy and 301 controls was performed using whole-genome sequencing (WGS) and PopSV.
Posted ContentDOI
Global characterization of copy number variants in epilepsy patients from whole genome sequencing
Jean Monlong,Simon Girard,Caroline Meloche,Maxime Cadieux-Dion,Danielle M. Andrade,Ron G. Lafreniere,Micheline Gravel,Dan Spiegelman,Alexandre Dionne-Laporte,Cyrus Boelman,Fadi F. Hamdan,Jacques L. Michaud,Guy A. Rouleau,Berge A. Minassian,Guillaume Bourque,Patrick Cossette +15 more
TL;DR: This genome-wide survey of copy number variants of epilepsy patients revealed an enrichment of rare exonic events in epilepsy patients, especially in genes with predicted loss-of-function intolerance, suggesting that comprehensive sequence-based profiling of CNVs could help explain a larger fraction of epilepsy cases.
Journal ArticleDOI
Le gène de la neurofibromatose de type 2
TL;DR: La neurofibromatose de type 2 (NF2) est une maladie hereditaire predisposant, principalement, au developpement de schwannomes vestibulaires et de meningiomes, which representent une proportion importante des tumeurs cerebrales.
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Ataxies, paraparésies spastiques et neuropathies héréditaires fréquentes dans l’Est du Canada
Nicolas Dupré,Nicolas Chrestian,Isabelle Thiffault,Bernard Brais,Guy A. Rouleau,Jean-Pierre Bouchard +5 more
TL;DR: The population of Eastern Canada is convinced to still allow the identification of new rare forms of hereditary ataxias, spastic parapareses and neuropathies as well as contribute to the uncovering of their mutated genes.