G
Guy A. Rouleau
Researcher at Montreal Neurological Institute and Hospital
Publications - 935
Citations - 75050
Guy A. Rouleau is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 129, co-authored 884 publications receiving 65892 citations. Previous affiliations of Guy A. Rouleau include Utrecht University & University of Helsinki.
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Journal ArticleDOI
Neurophysiological investigation of congenital mirror movements in a patient with agenesis of the corpus callosum.
Jean-François Lepage,Vincent Beaulé,Myriam Srour,Guy A. Rouleau,Alvaro Pascual-Leone,Maryse Lassonde,Hugo Théoret +6 more
TL;DR: The current data suggest a pattern of M1 excitability very similar to that found in patients with congenital mirror movements and no other motor abnormality.
Posted ContentDOI
Synaptic processes and immune-related pathways implicated in Tourette Syndrome
Fotis Tsetsos,Dongmei Yu,Dongmei Yu,Jae Hoon Sul,Jae Hoon Sul,Alden Y. Huang,Alden Y. Huang,Cornelia Illmann,Lisa Osiecki,Sabrina M. Darrow,Matthew E. Hirschtritt,Erica Greenberg,Kirsten R. Müller-Vahl,Manfred Stuhrmann,Yves Dion,Guy A. Rouleau,Harald N. Aschauer,Mara Stamenkovic,Monika Schlögelhofer,Paul Sandor,Cathy L. Barr,Marco A. Grados,Harvey S. Singer,Markus M. Nöthen,Johannes Hebebrand,Anke Hinney,Robert A. King,Thomas V. Fernandez,Csaba Barta,Zsanett Tarnok,Peter Nagy,Christel Depienne,Christel Depienne,Yulia Worbe,Andreas Hartmann,Cathy L. Budman,Renata Rizzo,Gholson J. Lyon,William M. McMahon,James R. Batterson,Danielle C. Cath,Irene A. Malaty,Michael S. Okun,Cheston M. Berlin,Douglas W. Woods,Paul C. Lee,Joseph Jankovic,Mary M. Robertson,Donald L. Gilbert,Lawrence W. Brown,Barbara J. Coffey,Andrea Dietrich,Pieter J. Hoekstra,Samuel Kuperman,Samuel H. Zinner,Michael Wagner,James A. Knowles,A. Jeremy Willsey,Jay A. Tischfield,Gary A. Heiman,Nancy J. Cox,Nelson B. Freimer,Nelson B. Freimer,Benjamin M. Neale,Benjamin M. Neale,Lea K. Davis,Giovanni Coppola,Giovanni Coppola,Carol A. Mathews,Jeremiah M. Scharf,Jeremiah M. Scharf,Jeremiah M. Scharf,Peristera Paschou +72 more
TL;DR: The indications of involvement of Ligand-gated Ion Channel Signaling reinforce the role of GABA in TS, while the association of Cell Adhesion and Transsynaptic Signaling gene set provides additional support for the role for adhesion molecules in neuropsychiatric disorders.
Journal ArticleDOI
No TARDBP Mutations in a French Canadian Population of Patients With Parkinson Disease
Edor Kabashi,Hussein Daoud,Jean-Baptiste Rivière,Paul N. Valdamanis,Patrick Bourgouin,Pierre Provencher,Emmanuelle Pourcher,Patrick A. Dion,Nicolas Dupré,Guy A. Rouleau +9 more
TL;DR: This review concludes that the prion protein gene codon 129 modulates clinical course of neurological Wilson disease and is associated with cognitive impairment in the elderly: the EVA study.
Journal ArticleDOI
RNA-Based Therapy Utilizing Oculopharyngeal Muscular Dystrophy Transcript Knockdown and Replacement.
Aida Abu-Baker,Nawwaf Kharma,Jonathan Perreault,Alanna Grant,Masoud Shekarabi,Claudia Maios,Michele Dona,Christian Neri,Patrick A. Dion,Alex Parker,Luc Varin,Guy A. Rouleau,Guy A. Rouleau +12 more
TL;DR: An optimized-codon wild-type PABPN1 (opt-PABPN1) is designed that is resistant to cleavage by hhRzs and miRNAs, and RNA replacement therapy represents an exciting approach for OPMD treatment.
Journal ArticleDOI
The role of the melanoma gene MC1R in Parkinson disease and REM sleep behavior disorder.
Ziv Gan-Or,Ziv Gan-Or,Noreen Mohsin,Simon Girard,Jacques Montplaisir,Amirthagowri Ambalavanan,Amirthagowri Ambalavanan,Stephanie Strong,Victoria Mallett,Sandra B. Laurent,Cynthia V. Bourassa,Michel Boivin,Michel Boivin,Mélanie Langlois,Isabelle Arnulf,Birgit Högl,Birgit Frauscher,Christelle Charley Monaca,Alex Desautels,Jean-François Gagnon,Ronald B. Postuma,Patrick A. Dion,Patrick A. Dion,Yves Dauvilliers,Nicolas Dupré,Roy N. Alcalay,Guy A. Rouleau,Guy A. Rouleau +27 more
TL;DR: The present study does not support a role for the MC1R p.R160W and other variants in susceptibility for PD or RBD and removes one study that introduced the heterogeneity.