Ladoke Akintola University of Technology

About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.

A review on synthesis, optimization, characterization and antibacterial application of gold nanoparticles synthesized from plants

Abstract: Gold nanoparticles (AuNPs) are one of the prominent metal nanoparticles (NPs) with a broad range of applications in various fields of science and technology. The demand for the use of AuNPs has been increasing on a regular basis. To meet such a demand, intensive research is required on optimizing synthesis approaches. Among various methods reported for the synthesis of AuNPs, biological methods using plant extract have been found to be simple, effective, cheap and environmental friendly because the gold salt is only reduced with biomolecules existing in plant extract. Various methods of AuNPs synthesis using different plant extracts have long been developed. Several techniques have been adopted in the characterization of the synthesized AuNPs. The antibacterial, antioxidant, anticancer and catalytic activities of AuNPs from plant extract have shown promising activities useful for several biomedical applications. This review focuses on the synthesis, optimization conditions, characterization and applications of biosynthesized AuNPs using plant extracts.

The tetracycline resistance gene tet39 is present in both Gram-negative and Gram-positive bacteria from a polluted river, Southwestern Nigeria.

Abstract: Aim: Previous analysis of tet39 suggests it may be present in other bacterial species. Hence, we investigated the host range of tet39 among bacterial from a poultry waste polluted river in Southwestern Nigeria. Methods and Results: Thirteen resistant bacterial isolated from the water and sediment of the polluted river was investigated for the presence of tetracycline resistance genes tetA, tetB, tetC, tet39 and the transposon integrase gene of the Tn916/1545 family by PCR. While tetA, tetB, tetC and integrase genes cannot be detected in any of the organisms, tet39 was detected in eight of the tested organisms including three Gram-positive species. Sequence analysis showed the genes have high sequence identities (≥99%) with tet39 of Acinetobacter sp. LUH5605, the first and only bacterial genus from which the gene has been reported to date. This is a novel observation. Conclusions: This study shows that apart from Acinetobacter, tet39 is present in other bacterial species tested in this study. Significance and Impact of the Study: This study adds to available information on the occurrence and distribution of tet39 among environmental bacteria and suggests that the gene has a broader host range than previously reported.

Green synthesis and characterization of zinc oxide nanoparticles using bashful ( Mimosa pudica ), leaf extract: a precursor for organic electronics applications

Abstract: Efforts has been intensified in the field of research for nanomaterials to bridge the gap for energy supply in this century. A plant- based material that may provide solutions to the current energy crisis may be found in nanomaterials. Green synthesis of nanoparticles using plant extract is gaining importance as an alternative to conventional chemical and physical method of synthesis, because of its simplicity and environmental friendliness. In this research we synthesized Zinc oxide nanoparticle (ZnO.NPs) using plant extracts and deposited using spin- coating technique. The obtained samples were characterized by UltraViolet–Visible spectrophotometer, Fourier Transform Infra-Red spectroscopy (FTIR), Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD) and Solar simulator for electrical properties. The maximum absorption peaks occurred at 235 nm, 250 nm, 270 nm, and 300 nm respectively but lower when compared with the bulk size that occurred at 350 nm and in the visible spectrum of the wavelength band. Band gap energy of zinc oxide nanoparticle at 500 rpm was 3.50 eV. ZnO.NPs FTIR spectrum was recorded in the range of 4000–500 cm−1. The synthesis ZnO NPs FTIR result shows Zn–O functional group was found at low wavenumber. SEM images of the samples give information on the morphology which are spherical and granular nature. The XRD pattern of synthesized nanoparticles shows that the substances only belong to ZnO since there is no diffraction peaks of other impurities and the average grain size of the particles was estimated to be 14.7 nm. ZnO.NPs thin film device under illumination has efficiency of 0.7%. Based on electrical properties of the fabricated thin film device, the parameter shows it could be suitable for photoanode of Dye sensitized solar cell.

Prevalence and Clinical Correlates of Metabolic Syndrome in Nigerians Living with Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome

Abstract: Background: Sub-Saharan Africa bears an inordinate burden of human immunodeficiency virus (HIV) infection/acquired immune deficiency syndrome (AIDS). Reports have shown increased prevalence of clustering of cardiovascular risk factors referred to as metabolic syndrome in treatment-naive patients and patients on highly active antiretroviral therapy (HAART). In view of the fact that metabolic syndrome is a heterogeneous disorder with substantial variability in the prevalence and component traits within and across populations and the dearth of publications on the prevalence and clinical correlates of metabolic syndrome in people living with HIV/AIDS (PLWHA) in Nigeria, this study was carried out to determine the prevalence and clinical correlates of metabolic syndrome among an HIV-infected outpatient population using the National Cholesterol Education Adult Treatment Panel III (NCEP ATP III), the International Diabetes Federation (IDF), and the Joint Interim Statement (JIS) definitions. We also soug...