Ladoke Akintola University of Technology

About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.

Dissemination of IncF plasmids carrying beta-lactamase genes in Gram-negative bacteria from Nigerian hospitals

Abstract: Introduction: Production of beta-lactamases is the predominant cause of resistance to beta-lactam antibiotics in Gram-negative bacteria. We investigated the diversity of plasmid-borne beta-lactamase genes and replicon type of the plasmids carrying the respective genes in Gram-negative bacteria recovered from clinical infection in Nigerian hospitals. Methodology: A total of 134 Gram-negative bacteria of 13 species were analyzed for antimicrobial susceptibility, phenotypic and genotypic detection of various beta-lactamases, and plasmid analysis, including replicon typing. Results: Of the 134 isolates, 111 (82.8%) contained beta-lactamases, while 28 (20.9%) carried extended-spectrum beta-lactamases. PCR and sequencing identified TEM-1 in 109 isolates (81.3%), SHV-1 in 33 isolates (24.6%), OXA-1 in 15 isolates (11.2%) and CTX-M enzymes (24 CTX-M-15 and 1 CTX-M-3) in 25 isolates (18.7%). Multiplex PCR showed that 6 isolates carried plasmidic AmpCs (ACT-1, DHA-1 and CMY-2); these enzymes were detected only in isolates possessing CTX-M beta-lactamases. Of 13 (76.9%) representative plasmids investigated in detail, 9 (69.2%) were self-transferable when selected by a beta-lactam and the plasmids once transferred coded for beta-lactam resistance. Replicon typing indicated IncF as the common vector encoding for beta-lactamases. Conclusions: The study showed a diversity of beta-lactamase genes disseminated by conjugative IncF plasmids in Gram-negative bacteria; TEM-1, SHV-1, OXA-1, CTX-M-15, CTX-M-3and plasmidic AmpC enzymes are in common circulation in Nigeria.

Kinetics and neuro-fuzzy soft computing modelling of river turbid water coag-flocculation using mango (Mangifera indica) kernel coagulant

Abstract: This study investigates kinetics and Adaptive Neuro-Fuzzy Modeling (ANFM) of river turbid water coagulation-flocculation (CF) process using mango kernel coagulant (MKC). CF experiments were...

Determinants of referral practices of clients by traditional birth attendants in Ilorin, Nigeria : original research

Abstract: A sizeable number of deliveries still take place with the assistance of Traditional Birth Attendants in Nigeria This study aims to determine the factors that determine the referral practices of the TBAs in Ilorin of high risk and complicated pregnancies This descriptive study was conducted among all the 162 registered TBAs in Ilorin that were traceable using pre-tested semi-structured interviewer-administered questionnaire About 90%, whose source of skill acquisition was by inheritance did not refer their clients appropriately compared with 48% of those whose source of skill acquisition was through formal training (p<005) The more the numbers of trainings, the more appropriate the referral (p<005) Having supervisory visit by qualified personnel is associated with appropriate referral practices (p<005) Regular training and re-training of TBAs with routine monitoring and supportive supervision will promote prompt referral of high risk and complicated pregnancies and deliveries Determinants des pratiques d'orientation des clientes chez les accoucheuses traditionnelles a Ilorin, Nigeria Bon nombre d'accouchements ont toujours lieu avec l'assistance des accoucheuses traditionnelles au Nigeria Cette etude a pour but de d'etablir les facteurs qui determinent les pratiques d'orientation des patientes chez les ATs a Ilorin des grossesse a haut risque et compliques Cette etude prescriptive a ete menee au sein de toutes les 162 SFTs qui sont a Ilorin qui ont ete trouvee grâce au questionnaire semi-structure et pre-teste qui a ete administree par l'enqueteur A peu pres 90% dont la source de l'acquisition des competences etaient a travers l'heritage n'ont pas oriente leurs patientes comme il faut envers les specialistes par rapport a 48% de celles dont la source de l'acquisition des competences a ete a travers une formation formelle (p < 0,05) Plus les nombres de formations plus les orientations vers les specialistes par le personnel qualifie est lie aux pratiques d'orientations appropriees (p < 0,05) La formation reguliere et la re-formation des SFTs avec la surveillance de routine et le controle de soutien vont encourager l'orientation rapide des grossesses et des accouchements a haut risque et compliquees

Determination of Residential Soil Gas Radon Risk Indices Over the Lithological Units of a Southwestern Nigeria University.

Abstract: Radiation dose from natural sources is mainly from exposure to radon in the environment. Radon has its origin from uranium-bearing bedrocks and overburden. In the present study, assessment of the level of radon over the three lithological units upon which the residential areas of ObafemiAwolowo University Campus, Ile-Ife (OAU) was situated was carried out. Soil gas radon concentration measurement was carried out at a constant depth of 0.80 m across the three lithologies (granite gneiss, grey gneiss and mica schist) using a RAD7 electronic radon detector. A total of 138 in-situ soil gas radon measurements were carried out. Obtained experimental data were analysed and summarised using descriptive and inferential statistics with statistical significance set at p < 0.05. A radon potential map was also developed using existing permeability data of the soils in the area. Soil radon concentration varied across the different lithologies ranging from 0.04 kBq/m3 – 190 kBq/m3 with a mean value of 14 kBq/m3. The mean value of Rn-222 concentration obtained in the three lithologies are 3.5 ± 5.9, 11.5 ± 25.8 and 28.4 ± 37.4 kBq/m3 for granite gneiss, grey gneiss and mica schist respectively. There is a statistically significant difference (p < 0.001) in the mean concentration of radon-222 measured on the three lithologies. The granite gneiss and grey gneiss lithologies have been designated into low radon index, while mica schist lithology has been designated as medium radon index. 34% of the sampled areas exhibit high radon risk based on Swedish risk criteria, thereby warranting protective actions.