Ladoke Akintola University of Technology

About: Ladoke Akintola University of Technology is a education organization based out in Ogbomoso, Nigeria. It is known for research contribution in the topics: Population & Adsorption. The organization has 2786 authors who have published 3066 publications receiving 36850 citations. The organization is also known as: Oyo State University of Technology & LAUTECH.

Wound-Healing and Potential Anti-Keloidal Properties of the Latex of Calotropis Procera (Aiton) Asclepiadaceae in Rabbits

Abstract: Calotropis Procera (CP) has been used in the management of toothache, fresh skin burns, gum bleeding as well as others to make it qualify as a medicinal plant. This study was designed to assess its wound-healing property in rabbits and its potentials for anti keloidal activity.Fresh latex of Calotropis were obtained and evaluated phytochemically. Fifteen male rabbits were used and four excisional wounds were created on each rabbit. The rabbits were divided into five groups of three each. Group 1 was the negative control and received no treatment. The wounds of group 2 animals were treated with 2mL of Calotropis latex; group 3 with 2mL honey; and group 4 with a mixture of 1ml honey and 1 mL of the latex. The animals in group 5 were given 2mg triamcinolone intramuscularly. All the groups had their wounds treated daily for 21 days. The wounds' diameters were measured on the day of wound creation, thereafter on days 7, 14 and 21 post wound creation. Biopsies of the wounds were taken on days 3 and 21 and viewed histologically. Phytochemical study of the latex revealed the presence of glycosides, tannins and alkaloids. The wounds were found to be significantly (p<0.05) reduced in groups treated with 50% latex in honey and triamcinolone, respectively, on day 7 post wound creation while there was a significant (p<0.05) reduction in wound surface area in all treated groups on days 14 and 21 post wound creation. Histological findings in untreated group showed thick bundle of collagen fibres some of which had broad based configurations, reminiscent of keloid. The group treated with 2mL of Calotropis latex revealed the presence of florid granulation tissues on day 3 while there was a marked reduction in quantity and size of collagen fibres on day 21 post wound creation which was comparable with what was seen for the triamcinolone-treated group.The general effect of Calotropis latex on wound-healing was noted. Likewise it's similarity to that of triamcinolone, an anti-keloidal agent; this makes it a probable candidate for future anti-keloidal study using a suitable model.

Kinetic Modelling and Half-Life Study on Bioremediation of Soil Co-Contaminated with Lubricating Motor Oil and Lead Using Different Bioremediation Strategies

Abstract: The focus of this study was to investigate the effect of nutrient supplement (urea fertilizer) and microbial species augmentation (mixed culture of Aeromonas, Micrococcus, and Serratia sp.) on biodegradation of lubricating motor oil (LMO) and lead uptake by the autochthonous microorganism in LMO and lead-impacted soil were investigated. The potential inhibitory effects of lead on hydrocarbon utilization were investigated over a wide range of lead concentrations (25–200 mg/kg) owing to the complex co-contamination problem frequently encountered in most sites. Under aerobic conditions, total petroleum hydrocarbons (TPH) removal was 45.3% in the natural attenuation microcosm while a maximum of 72% and 68.2% TPH removal was obtained in biostimulation and bioaugmentation microcosms, respectively. Lead addition, as lead nitrate, to soil samples reduced the number of hydrocarbon degraders in all samples by a wide range (11–52%) depending on concentration and similarly, the metabolic activities were affected as o...

Potentials of Snailshell as a Reinforcement for Discarded Aluminum Based Materials

Abstract: Snailshells and discarded aluminium based alloys have low economic values and are mostly considered as environmental pollutants. However, recycling them for further application in material processing can create significant economic value. Snailshell particles are known for their hardness, and thus useful as good alloying element for aluminium based pistons. In this paper, the potential of snailshell particles as reinforcement agent in Al/snailshell particulate composites is reported. Snailshell particles of weight fraction ranging from 16 to 48 wt.% and size of 200, 400 and 600 μm were added to aluminium obtained from discarded aluminum pistons during casting. The microstructures of the composites were examined under optical metallurgical microscope. The tensile strength and hardness were measured based on the experiments conducted using Box Behnken design. The results showed that, at 48 wt.% and 600 μm particle size, the tensile strength and hardness are maximum (236 MPa and 48.3 HRF, respectively) compared to the tensile strength of 92.4 MPa and hardness of 29.2 HRF for the unalloyed samples. These increments are attributed to the uniform distribution of snailshells in the ductile aluminum matrix. It is concluded that both the tensile strength and hardness are significantly enhanced, and snailshells can be used as a low-cost reinforcement for engineering applications.