Institution
Saint Louis University
Education•St Louis, Missouri, United States•
About: Saint Louis University is a education organization based out in St Louis, Missouri, United States. It is known for research contribution in the topics: Population & Health care. The organization has 18927 authors who have published 34895 publications receiving 1267475 citations. The organization is also known as: SLU & St. Louis University.
Topics: Population, Health care, Poison control, Transplantation, Medicine
Papers published on a yearly basis
Papers
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TL;DR: A positive association between ambient air pollution and increased BP and hypertension is indicated andGeographical and socio-demographic factors may modify the pro-hypertensive effects of air pollutants.
333 citations
University of Texas Southwestern Medical Center1, Columbia University2, Baylor College of Medicine3, Medical University of South Carolina4, Research Triangle Park5, Stanford University6, University of Pittsburgh7, University of Maryland, Baltimore8, University of Minnesota9, Brown University10, Emory University11, University of Arizona12, State University of New York Upstate Medical University13, Saint Louis University14, University of Kansas15
TL;DR: These 1-year open trial data found VNS to be well tolerated, suggesting a potential long-term, growing benefit in treatment-resistant depression, albeit in the context of changes in depression treatments.
332 citations
Washington University in St. Louis1, National Institutes of Health2, Johns Hopkins University3, University of California, San Diego4, Saint Louis University5, Baylor College of Medicine6, MetroHealth7, Cleveland Clinic8, Boston Children's Hospital9, Children's National Medical Center10, Duke University11, Indiana University12, Riley Hospital for Children13, University of California, San Francisco14, Virginia Commonwealth University15, Virginia Mason Medical Center16
TL;DR: Increased portal CI is associated with many clinical and pathologic features of progressive NAFLD in both adults and children, but not with ALT, autoantibodies, or lobular inflammation.
332 citations
TL;DR: Non-pharmacological interventions (including psychosocial/psychological counseling, interpersonal management and environmental management) should be attempted first, followed by the least harmful medication for the shortest time possible, as are the limitations and difficulties encountered when quantifying behavioral responses in clinical trials.
Abstract: Alzheimer's disease (AD) is a complex progressive brain degenerative disorder that has effects on multiple cerebral systems. In addition to cognitive and functional decline, diverse behavioral changes manifest with increasing severity over time, presenting significant management challenges for caregivers and health care professionals. Almost all patients with AD are affected by neuropsychiatric symptoms at some point during their illness; in some cases, symptoms occur prior to diagnosis of the dementia syndrome. Further, behavioral factors have been identified, which may have their origins in particular neurobiological processes, and respond to particular management strategies. Improved clarification of causes, triggers, and presentation of neuropsychiatric symptoms will guide both research and clinical decision-making. Measurement of neuropsychiatric symptoms in AD is most commonly by means of the Neuropsychiatric Inventory; its utility and future development are discussed, as are the limitations and difficulties encountered when quantifying behavioral responses in clinical trials. Evidence from clinical trials of both non-pharmacological and pharmacological treatments, and from neurobiological studies, provides a range of management options that can be tailored to individual needs. We suggest that non-pharmacological interventions (including psychosocial/psychological counseling, interpersonal management and environmental management) should be attempted first, followed by the least harmful medication for the shortest time possible. Pharmacological treatment options, such as antipsychotics, antidepressants, anticonvulsants, cholinesterase inhibitors and memantine, need careful consideration of the benefits and limitations of each drug class.
331 citations
TL;DR: Presence of insulin transcripts within specific neurons with extracellular secretion of the peptide suggests a specialized biological role in central mammalian neurons.
331 citations
Authors
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| Name | H-index | Papers | Citations |
|---|---|---|---|
| Douglas G. Altman | 253 | 1001 | 680344 |
| John E. Morley | 154 | 1377 | 97021 |
| Roberto Romero | 151 | 1516 | 108321 |
| Daniel S. Berman | 141 | 1363 | 86136 |
| Gregory J. Gores | 141 | 686 | 66269 |
| Thomas J. Smith | 140 | 1775 | 113919 |
| Richard T. Lee | 131 | 810 | 62164 |
| George K. Aghajanian | 121 | 277 | 48203 |
| Reza Malekzadeh | 118 | 900 | 139272 |
| Robert N. Weinreb | 117 | 1124 | 59101 |
| Leslee J. Shaw | 116 | 808 | 61598 |
| Thomas J. Ryan | 116 | 675 | 67462 |
| Josep M. Llovet | 116 | 399 | 83871 |
| Robert V. Farese | 115 | 473 | 48754 |
| Michael Horowitz | 112 | 982 | 46952 |