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Institution

University of Lorraine

EducationNancy, France
About: University of Lorraine is a education organization based out in Nancy, France. It is known for research contribution in the topics: Population & Context (language use). The organization has 11942 authors who have published 25010 publications receiving 425227 citations. The organization is also known as: Lorraine University.


Papers
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Journal ArticleDOI
TL;DR: A wide range of approaches like developing new generations of antibiotics, combination therapy, natural antibacterial substances and applying nanoparticulate systems have been explained, among them, antibiotic delivery via nanoparticles, has been attracted more attention recently, so discussed in present review.

210 citations

Journal ArticleDOI
TL;DR: In this article, the authors introduce new environmental constraints, namely carbon emission constraints, in multi-sourcing lot-sizing problems, which aim at limiting the carbon emission per unit of product supplied with different modes.

209 citations

Journal ArticleDOI
TL;DR: In this article, a wide-range investigation of the oxidation mechanism of ammonia was performed in a jet-stirred reactor and a flow reactor under lean conditions (0.01 ≤ Φ ≤ 0.375).
Abstract: A complete understanding of the mechanism of ammonia pyrolysis and oxidation in the full range of operating conditions displayed by industrial applications is one of the challenges of modern combustion kinetics. In this work, a wide-range investigation of the oxidation mechanism of ammonia was performed. Experimental campaigns were carried out in a jet-stirred reactor and a flow reactor under lean conditions (0.01 ≤ Φ ≤ 0.375), such to cover the full range of operating temperatures (500 K ≤ T ≤ 2000 K). Ammonia conversion and the formation of products and intermediates were analyzed. At the same time, the ammonia decomposition reaction, H-abstractions and the decomposition of the HNO intermediate were evaluated ab initio, and the related rates were included in a comprehensive kinetic model, developed according to a first-principles approach. Low-temperature reactor experiments highlighted a delayed reactivity of ammonia, in spite of the high amount of oxygen. A very slow increase in NH3 consumption rate with temperature was observed, and a full reactant consumption was possible only ∼150–200 K after the reactivity onset. The use of flux analysis and sensitivity analysis allowed explaining this effect with the terminating effect of the H-abstraction on NH3 by O2, acting in the reverse direction because of the high amounts of HO2. The central role of H2NO was observed at low temperatures (T < 1200 K), and H-abstractions from it by HO2, NO2 and NH2 were found to control reactivity, especially at higher pressures. On the other side, the formation of HNO intermediate via NH2 + O = HNO + H and its decomposition were found to be crucial at higher temperatures, affecting both NO/N2 ratio and flame propagation.

209 citations

Journal ArticleDOI
TL;DR: “How to perform contrast-enhanced ultrasound (CEUS)” provides general advice on the use of ultrasound contrast agents (UCAs) for clinical decision-making and reviews technical parameters for optimal CEUS performance.
Abstract: “How to perform contrast-enhanced ultrasound (CEUS)” provides general advice on the use of ultrasound contrast agents (UCAs) for clinical decision-making and reviews technical parameters for optimal CEUS performance CEUS techniques vary between centers, therefore, experts from EFSUMB, WFUMB and from the CEUS LI-RADS working group created a discussion forum to standardize the CEUS examination technique according to published evidence and best personal experience The goal is to standardise the use and administration of UCAs to facilitate correct diagnoses and ultimately to improve the management and outcomes of patients

208 citations

Journal ArticleDOI
TL;DR: Stroke rehabilitation including affected muscle strengthening and often stretching would first need to correct the postural asymmetric pattern by exploiting postural automatic processes in various particular motor tasks secondarily beneficial to gait.
Abstract: We reviewed neural control and biomechanical description of gait in both non-disabled and post-stroke subjects. In addition, we reviewed most of the gait rehabilitation strategies currently in use or in development and observed their principles in relation to recent pathophysiology of post-stroke gait. In both non-disabled and post-stroke subjects, motor control is organized on a task-oriented basis using a common set of a few muscle modules to simultaneously achieve body support, balance control, and forward progression during gait. Hemiparesis following stroke is due to disruption of descending neural pathways, usually with no direct lesion of the brainstem and cerebellar structures involved in motor automatic processes. Post-stroke, improvements of motor activities including standing and locomotion are variable but are typically characterized by a common postural behaviour which involves the unaffected side more for body support and balance control, likely in response to initial muscle weakness of the affected side. Various rehabilitation strategies are regularly used or in development, targeting muscle activity, postural and gait tasks, using more or less high-technology equipment. Reduced walking speed often improves with time and with various rehabilitation strategies, but asymmetric postural behaviour during standing and walking is often reinforced, maintained, or only transitorily decreased. This asymmetric compensatory postural behaviour appears to be robust, driven by support and balance tasks maintaining the predominant use of the unaffected side over the initially impaired affected side. Based on these elements, stroke rehabilitation including affected muscle strengthening and often stretching would first need to correct the postural asymmetric pattern by exploiting postural automatic processes in various particular motor tasks secondarily beneficial to gait.

208 citations


Authors

Showing all 12161 results

NameH-indexPapersCitations
Jonathan I. Epstein138112180975
Peter Tugwell129948125480
David Brown105125746827
Faiez Zannad10383990737
Sabu Thomas102155451366
Francis Martin9873343991
João F. Mano9782236401
Jonathan A. Epstein9429927492
Muhammad Imran94305351728
Laurent Peyrin-Biroulet9090134120
Athanase Benetos8339131718
Michel Marre8244439052
Bruno Rossion8033721902
Lyn March7836762536
Alan J. M. Baker7623426080
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202375
2022478
20213,153
20202,987
20192,799
20182,593