Institution
Washington State University
Education•Pullman, Washington, United States•
About: Washington State University is a education organization based out in Pullman, Washington, United States. It is known for research contribution in the topics: Population & Gene. The organization has 26947 authors who have published 57736 publications receiving 2341509 citations. The organization is also known as: WSU & Wazzu.
Topics: Population, Gene, Catalysis, Context (language use), Poison control
Papers published on a yearly basis
Papers
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TL;DR: This survey article enumerates, categorizes, and compares many of the methods that have been proposed to detect change points in time series, and presents some grand challenges for the community to consider.
Abstract: Change points are abrupt variations in time series data. Such abrupt changes may represent transitions that occur between states. Detection of change points is useful in modelling and prediction of time series and is found in application areas such as medical condition monitoring, climate change detection, speech and image analysis, and human activity analysis. This survey article enumerates, categorizes, and compares many of the methods that have been proposed to detect change points in time series. The methods examined include both supervised and unsupervised algorithms that have been introduced and evaluated. We introduce several criteria to compare the algorithms. Finally, we present some grand challenges for the community to consider.
788 citations
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TL;DR: The results suggest that lateral gene transfer between eubacteria subsequent to the origin of plastids has played a major role in the evolution of this pathway.
Abstract: Isopentenyl diphosphate (IPP) is the central intermediate in the
biosynthesis of isoprenoids, the most ancient and diverse class of
natural products. Two distinct routes of IPP biosynthesis occur in
nature: the mevalonate pathway and the recently discovered
deoxyxylulose 5-phosphate (DXP) pathway. The evolutionary history of
the enzymes involved in both routes and the phylogenetic distribution
of their genes across genomes suggest that the mevalonate pathway is
germane to archaebacteria, that the DXP pathway is germane to
eubacteria, and that eukaryotes have inherited their genes for IPP
biosynthesis from prokaryotes. The occurrence of genes specific to the
DXP pathway is restricted to plastid-bearing eukaryotes, indicating
that these genes were acquired from the cyanobacterial ancestor of
plastids. However, the individual phylogenies of these genes, with only
one exception, do not provide evidence for a specific affinity between
the plant genes and their cyanobacterial homologues. The results
suggest that lateral gene transfer between eubacteria subsequent to the
origin of plastids has played a major role in the evolution of this
pathway.
786 citations
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TL;DR: This review highlights some of the current drug and growth factor delivery approaches and critical issues using CaP particles, coatings, cements, and scaffolds towards orthopedic and dental applications.
785 citations
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TL;DR: The results of parsimony analyses of DNA sequences of the plastid genes rbcL and atpB and the nuclear 18S rDNA for 560 species of angiosperms and seven non-flowering seed plants are reported and show a well-resolved and well-supported phylogenetic tree for the angios perms for use in comparative biology.
Abstract: Comparative biology requires a firm phylogenetic foundation to uncover and understand patterns of diversification and evaluate hypotheses of the processes responsible for these patterns. In the angiosperms, studies of diversification in floral form, stamen organization, reproductive biology, photosynthetic pathway, nitrogen-fixing symbioses and life histories have relied on either explicit or implied phylogenetic trees. Furthermore, to understand the evolution of specific genes and gene families, evaluate the extent of conservation of plant genomes and make proper sense of the huge volume of molecular genetic data available for model organisms such as Arabidopsis, Antirrhinum, maize, rice and wheat, a phylogenetic perspective is necessary. Here we report the results of parsimony analyses of DNA sequences of the plastid genes rbcL and atpB and the nuclear 18S rDNA for 560 species of angiosperms and seven non-flowering seed plants and show a well-resolved and well-supported phylogenetic tree for the angiosperms for use in comparative biology.
782 citations
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TL;DR: The biosynthesis of the hydroxy, epoxy, and dicarboxylic acids of the polyesters from the common cellular fatty acids is elucidated and the function and possible practical implications of these polyester barriers are briefly discussed.
Abstract: Cutin, a biopolyester composed of hydroxy and epoxy fatty acids, is the barrier between the aerial parts of higher plants and their environment. Suberin a polymer containing aromatics and polyesters, functions as a barrier in underground parts, wound surfaces, and a variety of internal organs. The composition and probable structure of these polymers are discussed. The biosynthesis of the hydroxy, epoxy, and dicarboxylic acids of the polyesters from the common cellular fatty acids is elucidated. An extracellular enzyme transfers the hydroxy and epoxyacyl moieties from their coenzyme A derivatives to the growing polyester. The enzymes acting in the biodegradation of the polyesters have been isolated from fungi, pollen, and mammals and characterized. The function and possible practical implications of these polyester barriers are briefly discussed.
782 citations
Authors
Showing all 27183 results
Name | H-index | Papers | Citations |
---|---|---|---|
Anil K. Jain | 183 | 1016 | 192151 |
Martin Karplus | 163 | 831 | 138492 |
Herbert A. Simon | 157 | 745 | 194597 |
Suvadeep Bose | 154 | 960 | 129071 |
Rajesh Kumar | 149 | 4439 | 140830 |
Kevin Murphy | 146 | 728 | 120475 |
Jonathan D. G. Jones | 129 | 417 | 80908 |
Douglas E. Soltis | 127 | 612 | 67161 |
Peter W. Kalivas | 123 | 428 | 52445 |
Chris Somerville | 122 | 284 | 45742 |
Pamela S. Soltis | 120 | 543 | 61080 |
Yuehe Lin | 118 | 641 | 55399 |
Howard I. Maibach | 116 | 1821 | 60765 |
Jizhong Zhou | 115 | 766 | 48708 |
Farshid Guilak | 110 | 480 | 41327 |