Washington State University

About: Washington State University is a education organization based out in Pullman, Washington, United States. It is known for research contribution in the topics: Population & Gene. The organization has 26947 authors who have published 57736 publications receiving 2341509 citations. The organization is also known as: WSU & Wazzu.

Glucoreceptors controlling feeding and blood glucose: location in the hindbrain

Abstract: Microinfusion of 5-thioglucose into either the lateral or fourth cerebral ventricle caused increased feeding and hyperglycemia in rats when the cerebral aqueduct was unobstructed. If the aqueduct was obstructed and 5-thioglucose was infused into the fourth ventricle, increased feeding and hyperglycemia persisted, whereas feeding and hyperglycemia in response to lateral ventricle infusion were abolished. Drinking in response to infusion of angiotensin II into the lateral ventricle was not diminished by aqueduct obstruction. These results indicate that glucoreceptors that mediate feeding and hyperglycemia in response to cerebral glucoprivation are located in the caudal hindbrain and not in the hypothalamus where they have previously been sought.

Constructing arguments from multiple sources: Tasks that promote understanding and not just memory for text.

Abstract: In 2 experiments, understanding of historical subject matter was enhanced when students acted as historians and constructed their own models of an historical event. Providing students with information in a web site with multiple sources instead of a textbook chapter, and instructing them to write arguments instead of narratives, summaries, or explanations, produced the most integrated and causal essays with the most transformation from the original sources. Better performance on inference and analogy tasks provided converging evidence that students who wrote arguments from the web sources gained a better understanding than other students. A second experiment replicated the advantage of argument writing even when information was presented as an argument.

Macromolecular Trafficking Indicated by Localization and Turnover of Sucrose Transporters in Enucleate Sieve Elements

Abstract: The leaf sucrose transporter SUT1 is essential for phloem loading and long-distance transport of assimilates. Both SUT1 messenger RNA (mRNA) and protein were shown to be diurnally regulated and to have high turnover rates. SUT1 protein was detected by immunolocalization in plasma membranes of enucleate sieve elements (SEs) in tobacco, potato, and tomato. Analysis by in situ hybridization showed that SUT1 mRNA localizes mainly to the SE and is preferentially associated with plasmodesmata. Antisense inhibition of SUT1 expression under control of a companion cell (CC)-specific promoter indicated synthesis of SUT1 mRNA in the CC. These results provide evidence for targeting of plant endogenous mRNA and potentially SUT1 protein through phloem plasmodesmata and for sucrose loading at the plasma membrane of SE.