Tokyo Institute of Technology

About: Tokyo Institute of Technology is a education organization based out in Tokyo, Tôkyô, Japan. It is known for research contribution in the topics: Catalysis & Thin film. The organization has 46775 authors who have published 101656 publications receiving 2357893 citations. The organization is also known as: Tokyo Tech & Tokodai.

Lead-Free Highly Efficient Blue-Emitting Cs3Cu2I5 with 0D Electronic Structure

Abstract: Halide perovskites, including CsPbX3 (X = Cl, Br, I), have gained much attention in the field of optoelectronics However, the toxicity of Pb and the low photoluminescence quantum yield (PLQY) of these perovskites hamper their use In this work, new halide materials that meet the requirements of: (i) nontoxicity, (ii) high PLQY, and (iii) ease of fabrication of thin films via the solution process are explored In particular, copper(I) halide compounds with low-dimensional electronic structures are considered Cs3 Cu2 I5 has a 0D photoactive site and exhibits blue emission (≈445 nm) with very high PLQYs of ≈90 and ≈60% for single crystals and thin films, respectively The large exciton binding energy of ≈490 meV explains well the 0D electronic nature of Cs3 Cu2 I5 Blue electroluminescence of Pb-free halides is demonstrated using solution-derived Cs3 Cu2 I5 thin films

Deep-sea mud in the Pacific Ocean as a potential resource for rare-earth elements

Abstract: World demand for rare-earth elements and the metal yttrium is rapidly increasing. An analysis of more than 2,000 seafloor sediment samples suggests that deep-sea mud constitutes a highly promising giant resource for these elements.

Mutations in the deubiquitinase gene USP8 cause Cushing's disease

Abstract: Cushing's disease is caused by corticotroph adenomas of the pituitary. To explore the molecular mechanisms of endocrine autonomy in these tumors, we performed exome sequencing of 10 corticotroph adenomas. We found somatic mutations in the USP8 deubiquitinase gene in 4 of 10 adenomas. The mutations clustered in the 14-3-3 protein binding motif and enhanced the proteolytic cleavage and catalytic activity of USP8. Cleavage of USP8 led to increased deubiqutination of the EGF receptor, impairing its downregulation and sustaining EGF signaling. USP8 mutants enhanced promoter activity of the gene encoding proopiomelanocortin. In summary, our data show that dominant mutations in USP8 cause Cushing's disease via activation of EGF receptor signaling.

Classification Theory of Polarized Varieties

Abstract: A polarised variety is a modern generalization of the notion of a variety in classical algebraic geometry. It consists of a pair: the algebraic variety itself, together with an ample line bundle on it. Using techniques from abstract algebraic geometry that have been developed over recent decades, Professor Fujita develops classification theories of such pairs using invariants that are polarised higher-dimensional versions of the genus of algebraic curves. The heart of the book is the theory of D-genus and sectional genus developed by the author, but numerous related topics are discussed or surveyed. Proofs are given in full in the central part of the development, but background and technical results are sometimes just sketched when the details are not essential for understanding the key ideas. Readers are assumed to have some background in algebraic geometry, including sheaf cohomology, and for them this work will provide an illustration of the power of modern abstract techniques applied to concrete geometric problems. Thus the book helps the reader not only to understand about classical objects but also modern methods, and so it will be useful not only for experts but also non-specialists and graduate students.