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4. Modelling Survival Data in Medical Research

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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.

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Citations
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Outcomes of Blalock-Taussig shunts in current era: A single center experience.

TL;DR: The commonest indication for a modified Blalock-Taussig shunt in the current era was single ventricle palliation, andMorbidity and mortality was considerable, partly explained by the higher at risk population.
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Opportunistic infection and immunologic function in patients with human immunodeficiency virus-associated non-Hodgkin's lymphoma treated with chemotherapy

TL;DR: Treatment of patients who have HIV-associated NHL with a non-steroid-containing chemotherapy regimen was associated with a significant and sustained reduction in the CD4 lymphocyte count and a twofold increase in the risk of developing opportunistic infection.
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A Comparison between Accelerated Failure-time and Cox Proportional Hazard Models in Analyzing the Survival of Gastric Cancer Patients.

TL;DR: Although most cancer researchers tend to use proportional hazard model, accelerated failure-time models in analogous conditions — as they do not require proportional hazards assumption and consider a parametric statistical distribution for survival time — will be credible alternatives to proportional hazard models.
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Baseline factors associated with incident HIV and STI in four microbicide trials.

TL;DR: Although there was little evidence of associations between baseline STIs and incident HIV, they were strongly associated with incident STIs, and younger age was robustly associated with multiple STI outcomes in multivariable analyses.
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Appropriateness of anthropometric obesity indicators in assessment of coronary heart disease risk among Finnish men and women.

TL;DR: Abdominal obesity has an effect on CHD incidence independently of general obesity, and WHR was the best predictor ofCHD incidence in the data.
References
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Journal ArticleDOI

Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis

TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
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Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma

TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
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Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma

TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.