Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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Stroke after Radiotherapy to Treat Head and Neck Cancer - What is the Risk?
TL;DR: Thesis (Master, Community Health & Epidemiology) -- Queen's University, 2014-09-15 12:25:16.705
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Sobrevivencia en el empleo de los trabajadores de enfermería en una institución hospitalaria pública
TL;DR: In this article, o presente trabalho estima o tempo de ''sobrevivencia'' no emprego dos trabalhadores de enfermagem, apos sua admissao em um hospital publico, como um dos indicators of rotatividade.
Journal ArticleDOI
Encouraging Students to Think Critically: Regression Modelling and Goodness-of-Fit
TL;DR: In this article, the authors highlight important considerations that should be taken into account when teaching students to check for inadequacies of a given linear, nonlinear or logistic regression models.
Journal ArticleDOI
Risk of Acute Liver Injury With Antiretroviral Therapy by Viral Hepatitis Status.
Charitha Gowda,Charitha Gowda,Craig Newcomb,Qing Liu,Dena M. Carbonari,James D. Lewis,Kimberly A. Forde,David S. Goldberg,K. Rajender Reddy,Jason Roy,Amy R. Marks,Jennifer L. Schneider,Jay R. Kostman,Janet P. Tate,Joseph K. Lim,Amy C. Justice,Matthew Bidwell Goetz,Douglas A. Corley,Vincent Lo Re +18 more
TL;DR: Within the year after ART initiation, aminotransferase elevations were infrequently observed and rarely led to severe ALI, and protease inhibitor use was associated with a higher risk of aminOTransferases elevations among viral hepatitis-coinfected patients.
Journal ArticleDOI
Explaining survival differences between two consecutive studies with allogeneic stem cell transplantation in patients with chronic myeloid leukemia.
Markus Pfirrmann,Susanne Saussele,Andreas Hochhaus,Andreas Reiter,Ute Berger,Dieter K. Hossfeld,Christoph Nerl,Christof Scheid,Karsten Spiekermann,Jiri Mayer,Andrzej Hellmann,Klaus Lechner,Christiane Falge,Herbert G. Sayer,Donald Bunjes,Arnold Ganser,Dietrich W. Beelen,Helen Baldomero,Urs Schanz,Hermann Heimpel,Hans-Jochem Kolb,Joerg Hasford,Alois Gratwohl,Rüdiger Hehlmann +23 more
TL;DR: Discrepancies in influential prognostic factors explained the different post-transplant survival probabilities between the studies, and the significance of calendar time suggests a lack of consistency of transplantation practice over time.
References
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Journal ArticleDOI
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
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Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.