Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Child survival gains in Tanzania: analysis of data from demographic and health surveys
Honorati Masanja,Don de Savigny,Paul Smithson,Joanna Schellenberg,Theopista John,Conrad Mbuya,Gabriel Upunda,Ties Boerma,Cesar G. Victora,Thomas J. Smith,Hassan Mshinda +10 more
TL;DR: Tanzania could attain MDG 4 if this trend of improved child survival were to be sustained, and investment in health systems and scaling up interventions can produce rapid gains in child survival.
Journal Article
Dental endosseous implant assessments in a type 2 diabetic population: a prospective study.
John W. Olson,Alan F. Shernoff,Jeffrey L. Tarlow,John A. Colwell,James P. Scheetz,Stephen F. Bingham +5 more
TL;DR: This study supports the use of dental implants in type 2 diabetic patients and finds only duration of diabetes and implant length to be statistically significant predictors of implant failure.
Journal ArticleDOI
"Successful aging": effect of subclinical cardiovascular disease.
Anne B. Newman,Alice M. Arnold,Barbara L. Naydeck,Linda P. Fried,Gregory L. Burke,Paul L. Enright,John S. Gottdiener,Calvin H. Hirsch,Daniel H. O'Leary,Russell P. Tracy +9 more
TL;DR: There is a graded relationship between the extent of vascular disease measured noninvasively and the likelihood of maintaining intact health and function and prevention of subclinical vascular disease may increase the quality and the quantity of years in late life.
Journal ArticleDOI
Estrogen Receptor and Progesterone Receptor As Predictive Biomarkers of Response to Endocrine Therapy: A Prospectively Powered Pathology Study in the Tamoxifen and Exemestane Adjuvant Multinational Trial
John M. S. Bartlett,Cassandra Brookes,T Robson,Cornelis J.H. van de Velde,Lucinda Billingham,Fiona Campbell,Margaret Grant,Annette Hasenburg,Elysée T.M. Hille,Charlene Kay,Dirk G. Kieback,Hein Putter,Christos Markopoulos,Elma Meershoek-Klein Kranenbarg,Elizabeth Mallon,Luc Dirix,Caroline Seynaeve,Daniel Rea +17 more
TL;DR: Preference exemestane versus tamoxifen treatment benefit was not predicted by PgR expression; conversely, patients with ER-rich tumors may derive additional benefit from exemstane, and Quantitative analysis of ER and PGR expression provides highly significant information on risk of early relapse during treatment.
Journal ArticleDOI
Statistical and data reporting guidelines for the European Journal of Cardio-Thoracic Surgery and the Interactive CardioVascular and Thoracic Surgery
Graeme L. Hickey,Graeme L. Hickey,Graeme L. Hickey,Joel Dunning,Burkhardt Seifert,Gottfried Sodeck,Matthew J. Carr,Hans Ulrich Burger,Friedhelm Beyersdorf +8 more
TL;DR: To facilitate authors considering submitting a manuscript and to make it clearer about the expectations of the statistical reviewers, up-to-date guidelines for authors on statistical and data reporting specifically in these journals are presented.
References
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Journal ArticleDOI
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.