Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Leanness and lung cancer risk: fact or artifact?
TL;DR: The association between leanness and lung cancer mortality is not causal but rather is an artifact of the effects of smoking and preexisting disease, which may cause a spurious association between low body mass index and fatal lung cancer.
Journal ArticleDOI
The Extent that Noncompliance with the Ten Steps to Successful Breastfeeding Influences Breastfeeding Duration
TL;DR: Prevalent US maternity care practices do not include all of the Ten Steps, and this lack of care may be associated with poor establishment of the physiological feedback systems that support sustained breastfeeding.
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Connecting Events in Time to Identify a Hidden Population: Birth Mothers and Their Children in Recurrent Care Proceedings in England
Karen Broadhurst,Bachar Alrouh,Emily Yeend,Judith Harwin,Mike Shaw,Mark Pilling,Claire Mason,Sophie Kershaw +7 more
TL;DR: Findings indicate that the family justice system recyclessizeablepercentage of women (24percent) throughrepeatepisodes of care proceedings, with young women aged sixteen to nineteen years most at risk of recurrence.
Journal ArticleDOI
Use of Risk Models to Predict Death in the Next Year Among Individual Ambulatory Patients With Heart Failure.
Larry A. Allen,Daniel D. Matlock,Susan M. Shetterly,Stanley Xu,Wayne C. Levy,Laura B. Portalupi,Colleen K. McIlvennan,Jerry H. Gurwitz,Eric S. Johnson,David H. Smith,David J. Magid +10 more
TL;DR: Although heart failure risk models perform reasonably well at the population level, they do not reliably predict which individual patients will die in the next year.
Journal Article
Cox Regression Models with Nonproportional Hazards Applied to Lung Cancer Survival Data
N. Ata,M. T. Sözer +1 more
TL;DR: The results are illustrated by an analysis of lung cancer data in order to compare these methods with respect to Cox regression model in the presence of nonproportional hazards.