Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Natural products for malaria vector control: flora, fish and fungi
TL;DR: This paper focuses on malaria vector control options available to rural African communities in the context of an integrated vector management strategy: a review of Azadirachta indica (the neem tree) and edible fish.
Dissertation
Epidemiología, características clínicas y morbi-mortalidad del hipopituitarismo en el Área Sanitaria de Santiago de Compostela
TL;DR: La disgenesia de tallo hipofisario es un hipopituitarismo congenito de grado variable asociado with alteraciones del desarrollo del area selar (adelgazamiento o la ausencia completa del tallo hipsario asociados o no con aplasia o hipoplasia of the hipofISis anterior y/o con neurohipofisis ectopica).
Frailty multi-state models for the analysis of survival data from multicenter clinical trials
TL;DR: In this paper, the authors proposed the incorporation of nested frailties in the transition-specific hazard function, and developed and evaluated both parametric and semi-parametric inference.
Journal ArticleDOI
Outliers in survival analysis
Durdu Karasoy,Nuray Tuncer +1 more
TL;DR: Yasam cozumlemesi, tanimlanan herhangi bir olayin ortaya cikmasina kadar gecen surenin incelenmesinde kullanilan istatistiksel yontemler butunudur as discussed by the authors.
Efficient design and modeling strategies for follow-up studies with time-varying covariates
TL;DR: In this paper, the authors investigate efficient designs and analysis methods in follow-up studies with longitudinal measurements and propose a method for selecting optimal subcohorts for a new longitudinal covariate measurement if we cannot afford to measure the entire cohort.