Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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Journal ArticleDOI
Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Book ChapterDOI
Joint Analysis of Longitudinal Quality of Life and Survival Processes
TL;DR: This chapter shows how quality of life can be analyzed by defining an event corresponding to its definitive deterioration by building a semi-parametric semi-Markovian multi-states model and an analysis based on a joint model of the continuous longitudinal (QoL) variable and the time of dropout or death.
Journal ArticleDOI
Distribution, size, and shape of abdominal aortic calcified deposits and their relationship to mortality in postmenopausal women
Melanie Ganz,Marleen de Bruijne,Erik B. Dam,P.C. Pettersen,Morten A. Karsdal,Claus Christiansen,Mads Nielsen +6 more
TL;DR: Morphometric markers of AAC quantified from radiographs may be a useful tool for screening and monitoring risk of CVD mortality in postmenopausal women and after adjusting for traditional risk factors.
Journal ArticleDOI
Long-Term Survival Analysis of the Canadian Lung Volume Reduction Surgery Trial
TL;DR: A 16-month survival advantage and a 20% reduction in mortality was observed in the LVRS group as compared with the best medical care group, and although clinically meaningful, these differences were not statistically significant.
Journal ArticleDOI
Patients and surgery-related factors that affect time to recovery of consciousness in adult patients undergoing elective cardiac surgery
TL;DR: It was demonstrated that older age, male gender, lower body mass index, higher preoperative blood urea nitrogen level, and longer bypass duration were independent risk factors of delayed emergence after elective cardiac surgery.
Journal ArticleDOI
Optimization of pyrethroid and repellent on fabrics against Stegomyia albopicta (=Aedes albopictus) using a microencapsulation technique
TL;DR: Fabrics impregnated by microencapsulated mixtures gained extended washing durability compared with those treated with a conventional dipping method and represents a promising method for the future impregnation of bednet, curtain and combat uniform materials.