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4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Impact Assessment of Remote Control and Preventive Maintenance on the Failure Rate of a Disconnector Population
TL;DR: In this article, the authors presented the impact of different explanatory variables, such as remote control availability and conducted preventive maintenance, among others, on failure statistics of a disconnector population in Sweden using the proportional hazard model.
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A new log-location regression model: estimation, influence diagnostics and residual analysis
TL;DR: In this paper, a log-linear regression model based on the odd log-logistic generalized half-normal distribution is introduced, including explicit expressions for the density function, quantile and generating functions and ordinary moments.
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Prostate cancer with large glands treated with 3- dimensional computerized tomography guided pararectal brachytherapy: up to 8 years of followup
Panos G. Koutrouvelis,Niko Lailas,Stuart Katz,James T. Sehn,Guillermo Gil-Montero,Nabil Khawand +5 more
TL;DR: The 3-dimensional computerized tomography guided pararectal permanent implant results in a high level of biochemical control with low morbidity at 2 to 8 years in patients with prostate cancer who have a large prostate.
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Sequential Bilateral Corneal Transplantation and Graft Survival
Bernhard Steger,Bernhard Steger,Elinor Curnow,Robert Cheeseman,Vito Romano,Vito Romano,Abigail Kaye,Mark N. A. Jones,Stephen B. Kaye,Stephen B. Kaye +9 more
TL;DR: A transplant in the second eye was associated with a reduced risk of graft failure in the first eye, independent of inter-transplant time, and this effect was pronounced following an EK in theFirst eye, where the risk of failure was reduced by 70%.
Journal ArticleDOI
Measurement of temporal regional cerebral perfusion with single-photon emission tomography predicts rate of decline in language function and survival in early Alzheimer's disease.
TL;DR: It is concluded that left temporal rCBF predicts decline in language function and survival in patients with early probable Alzheimer’s disease, with a threshold effect of low r CBF and high risk of mortality.