Journal ArticleDOI
4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
Citations
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combining estimates of interest in prognostic modelling studies after multiple imputation: current practice and guidelines
TL;DR: The proposed simple guidelines for combining estimates after MI may lead to a wider and more appropriate use of MI in future prognostic modelling studies.
Journal ArticleDOI
Blood pressure and cardiovascular disease in the Asia Pacific region.
Carlene M.M. Lawes,Anthony Rodgers,Derrick A Bennett,Varsha Parag,Il Suh,Hirotsugu Ueshima,Stephen MacMahon +6 more
TL;DR: Blood pressure was at least as strongly associated with cardiovascular events in Asian populations compared to Australasian populations and considerable potential benefit of blood pressure lowering down to levels of at least 115 mmHg systolic blood pressure is seen.
Journal ArticleDOI
Variations in Lung Cancer Risk Among Smokers
Peter B. Bach,Michael W. Kattan,Mark D. Thornquist,Mark G. Kris,Ramsey C. Tate,Matt J. Barnett,Lillian J. Hsieh,Colin B. Begg +7 more
TL;DR: The risk of lung cancer varies widely among smokers, and accurate risk prediction may help individuals who are contemplating voluntary screening to balance the potential benefits and risks.
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Timing of identification among children with an autism spectrum disorder: findings from a population-based surveillance study.
Paul T. Shattuck,Maureen S. Durkin,Matthew J. Maenner,Craig J. Newschaffer,David S. Mandell,Lisa D. Wiggins,Li Ching Lee,Catherine Rice,Ellen Giarelli,Russell S. Kirby,Jon Baio,Jennifer Pinto-Martin,Christopher Cuniff +12 more
TL;DR: The large gap between the age at which children can be identified and when they actually are identified suggests a critical need for further research, innovation, and improvement in this area of clinical practice.
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Association Among SF36 Quality of Life Measures and Nutrition, Hospitalization, and Mortality in Hemodialysis
TL;DR: In patients on MHD the SF36 appears to have significant associations with measures of nutritional status, anemia, and clinical outcomes, including prospective hospitalization and mortality, even though obesity, unlike undernutrition, is not generally an indicator of poor outcome in MHD.
References
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
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Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.