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4. Modelling Survival Data in Medical Research

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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.

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Getting more out of survival data by using the hazard function.

TL;DR: The hazard function tracks the instantaneous failure rate over time among the surviving patients and can be readily estimated with available software and illustrated how these estimates can be used in conjunction with estimates of the survival function to glean clinically relevant information from survival data.
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Is surveillance imaging effective for detecting surgically treatable recurrences in patients with melanoma? A comparative analysis of stage-specific surveillance strategies.

TL;DR: The effectiveness of routine surveillance imaging for detecting treatable melanoma recurrences is limited and even in patients with stage III disease, only minimal gains in life expectancy were achieved.
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A comparison of methods for fixed effects meta-analysis of individual patient data with time to event outcomes:

TL;DR: Comparisons of commonly used methods for fixed effects meta-analysis of individual patient time-to-event data suggest that under normal conditions all three methods provide similar results.
Journal Article

Hip fracture evaluation with alternatives of total hip arthroplasty versus hemiarthroplasty (HEALTH): Protocol for a multicentre randomised trial

TL;DR: The HEALTH trial as discussed by the authors compared outcomes following total hip arthroplasty (THA) versus hemiarthroplastic surgery (HA) in patients with displaced femoral neck fractures.
References
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis

TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
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Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma

TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
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Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma

TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.