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4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Use of implantable loop recorders in the diagnosis and management of syncope
TL;DR: LR significantly increased the rate of diagnosis in an unselected Western population with recurrent syncope and there was a significant decrease in the rates of hospitalisation and investigation in patients receiving an ILR.
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Patch leaving decision rules and the Marginal Value Theorem: an experimental analysis and a simulation model.
TL;DR: The patch exploitation strategy of females of the insect parasitoid Trichogramma brassicae was studied on patches containing different proportions of hosts that were previously attacked by conspecific females, and a set of patch leaving rules seems to provide them with a sufficient way to reach the predictions of the Charnov model.
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One-year contraceptive continuation and pregnancy in adolescent girls and women initiating hormonal contraceptives.
Tina R. Raine,Anne Foster-Rosales,Ushma D. Upadhyay,Cherrie B. Boyer,Beth A. Brown,Abby Sokoloff,Cynthia C. Harper +6 more
TL;DR: The patch and the ring may not be better options than the pill or depot medroxyprogesterone acetate for women at high risk for unintended pregnancy, and the need for counseling interventions to improve contraceptive continuation is highlighted.
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Activities and participation of 9- to 13-year-old children with cerebral palsy
Jeanine M Voorman,Annet J. Dallmeijer,Carlo Schuengel,Dirk L. Knol,Gustaaf J. Lankhorst,Jules G. Becher +5 more
TL;DR: Activities and participation in children with cerebral palsy can, to a large extent, be explained by only a few associated factors.
Journal ArticleDOI
The council presidency in the European Union: responsibility with power
TL;DR: In this article, the conditions under which presidents influence the timing and content of decision outcomes in the legislative arena are investigated and it is shown that decision outcomes are significantly more favourable to presidents in the chair at the time of adoption than to other Member States, even after controlling for other factors that influence bargaining success.