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4. Modelling Survival Data in Medical Research
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This article is published in Journal of The Royal Statistical Society Series A-statistics in Society.The article was published on 1995-01-01. It has received 1092 citations till now. The article focuses on the topics: Medical research.read more
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Mineral Metabolism, Mortality, and Morbidity in Maintenance Hemodialysis
Geoffrey A. Block,Preston S. Klassen,J. Michael Lazarus,Norma J. Ofsthun,Edmund G. Lowrie,Glenn M. Chertow +5 more
TL;DR: Hyperphosphatemia and hyperparathyroidism were significantly associated with all-cause, cardiovascular, and fracture-related hospitalization, and the population attributable risk percentage for disorders of mineral metabolism was 17.5%, owing largely to the high prevalence of hyperph phosphatemia.
Journal ArticleDOI
Overall Survival and Updated Results for Sunitinib Compared With Interferon Alfa in Patients With Metastatic Renal Cell Carcinoma
Robert J. Motzer,Thomas E. Hutson,Piotr Tomczak,M. Dror Michaelson,Ronald M. Bukowski,Stéphane Oudard,Sylvie Negrier,Cezary Szczylik,Roberto Pili,Georg A. Bjarnason,Xavier Garcia-del-Muro,Jeffrey A. Sosman,Ewa Solska,George Wilding,John A. Thompson,Sindy T. Kim,Isan Chen,Xin Huang,Robert A. Figlin +18 more
TL;DR: Sunitinib demonstrates longer overall survival compared with IFN-alpha plus improvement in response and progression-free survival in the first-line treatment of patients with metastatic RCC, highlighting an improved prognosis in patients with RCC in the era of targeted therapy.
Journal ArticleDOI
Neoadjuvant Chemotherapy or Primary Surgery in Stage IIIC or IV Ovarian Cancer
Ignace Vergote,Claes G. Tropé,Frédéric Amant,G.B. Kristensen,Tom Ehlen,N Johnson,René H.M. Verheijen,Maria E. L. van der Burg,A. J. Lacave,Pierluigi Benedetti Panici,Gemma G. Kenter,Antonio Casado,Cesar Mendiola,Corneel Coens,Leen Verleye,Gavin Stuart,Sergio Pecorelli,Nicholas Reed +17 more
TL;DR: Neoadjuvant chemotherapy followed by interval debulking surgery was not inferior to primary debulked surgery followed by chemotherapy as a treatment option for patients with bulky stage IIIC or IV ovarian carcinoma in this study.
Journal ArticleDOI
Survival and Prognostic Stratification of 670 Patients With Advanced Renal Cell Carcinoma
TL;DR: Five prognostic factors for predicting survival were identified and used to categorize patients with metastatic RCC into three risk groups, for which the median survival times were separated by 6 months or more.
References
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Markers for predicting mortality in untreated HIV-infected children in resource-limited settings: a meta-analysis
Trinh Duong,Diana M. Gibb,David Dunn,C Chintu,Mark F. Cotton,Brian Eley,J Ellis,C. Giaquinto,Stephen M. Graham,P Msellati,Tammy Meyers,Harry Moultrie,Mulenga,M Nanyonga,J Pinto,Paul Roux,Ralf Weigel,Heather J. Zar +17 more
TL;DR: CD4 measurements are the most important indicator of mortality and wider access to affordable tests is needed in resource-limited settings, and Evaluation of antiretroviral initiation in children also needs to consider weight-for-age and haemoglobin.
Journal ArticleDOI
Residential neighbourhood greenspace is associated with reduced risk of incident diabetes in older people: a prospective cohort study
Alice M. Dalton,Andrew Jones,Stephen J. Sharp,Andrew J. M. Cooper,Simon J. Griffin,Nicholas J. Wareham +5 more
TL;DR: Greener home neighbourhoods may protect against risk of diabetes in older adults, although this study does not support a mediation role for physical activity.
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Screening for pressure ulcer risk in an acute care hospital: development of a brief bedside scale.
Thomas V. Perneger,Thomas V. Perneger,Anne Claire Raë,Jean-Michel Gaspoz,François Borst,Olga Vitek,Céliane Héliot +6 more
TL;DR: This brief bedside pressure ulcer prediction tool for patients admitted to acute care hospitals performed well in an acute care setting and may facilitate the implementation of pressure ulcers prevention interventions.
Journal ArticleDOI
Association between single nucleotide polymorphisms in the XRCC1 and RAD51 genes and clinical radiosensitivity in head and neck cancer.
Nicola Pratesi,Monica Mangoni,Irene Mancini,Fabiola Paiar,Lisa Simi,Lorenzo Livi,S. Cassani,Michela Buglione,Salvatore Grisanti,Camillo Almici,Caterina Polli,Calogero Saieva,Stefano Maria Magrini,Giampaolo Biti,Mario Pazzagli,Claudio Orlando +15 more
TL;DR: The findings showed an association between genetic polymorphisms, XRCC1 c.1196A>G and RAD51 c.-3429 G>C, and the development of radiation-induced toxicities in SCCHN patients.
Journal ArticleDOI
Early weaning of HIV-exposed uninfected infants and risk of serious gastroenteritis: Findings from two perinatal HIV prevention trials in Kampala, Uganda.
Carolyne Onyango-Makumbi,Danstan Bagenda,Antony Mwatha,Saad B. Omer,Philippa Musoke,Francis Mmiro,Sheryl Zwerski,Brenda Asiimwe Kateera,Maria Musisi,Mary Glenn Fowler,J. Brooks Jackson,Laura Guay +11 more
TL;DR: Early breastfeeding cessation seen in the HIVIGLOB/NVP trial was associated with increased risk of serious gastroenteritis among HIV-exposed uninfected infants when compared with later breastfeeding cessation inThe HIVNET 012 trial.